Cardiac PET and PET/CT Imaging (eBook)

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2007 | 2007
XVIII, 470 Seiten
Springer New York (Verlag)
978-0-387-38295-1 (ISBN)

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This book presents the most up-to-date information on the practice of cardiac PET and hybrid PET/CT. Each chapter takes a step-by-step approach, from basic principles of instrumentation, imaging, and protocols to advanced discussions of current and future clinical applications. Coverage also includes a perspective on other emerging imaging modalities, such as MRI, and the relative role of each. In addition, the volume details the technical aspects of cardiac PET and PET/CT imaging. A library of original cases completes the text by illustrating interpretation and technical challenges in cardiac PET and hybrid PET/CT.


When the history of medicine in the latter half of the twentieth century is written, the advances in cardiovascular diagnosis, therapy, and prevention will stand out as one of the most important achievements. Although the age-corrected death rate secondary to coronary artery disease has declined substantially in industri- ized nations during this period, the prevalence of these conditions remains stubbornly high because of the aging of the population. Importantly, the incidence of coronary events and of one of their most important sequelae-heart failure-is rising ala- ingly in the developing world. When viewed from a global perspective, cardiovascular disease is assuming a progressively greater importance, and it is estimated that by 2025 it will be, for the ? rst time in human history, the most common cause of death. Clearly, rather than resting on the laurels of our achievements, an intensi? cation of the battle against cardiovascular disease must now be undertaken. Cardiovascular imaging will, without question, play a critical role in this battle. The appropriate sel- tion of therapeutic measures, be they pharmacologic, catheter-based, surgical, alte- tions in lifestyles, or some combination of these, depends on accurate assessments of both cardiac structure and function. Increasingly, the changes that dictate mana- ment are quite subtle and require a level of precision that was not available to cli- cians heretofore.

Foreword 6
Preface 8
Contents 10
Contributors 13
Instrumentation and Principles of Imaging 17
Instrumentation and Principles of Imaging: PET 18
Instrumentation and Principles of CT 34
Integrated PET/ CT 49
Principles of Quantitation in Cardiac PET 61
General Considerations for Performing PET and Integrated PET/ CT 86
Radiopharmaceuticals for Clinical Cardiac PET Imaging 87
Iodinated Contrast Agents for Cardiac CT 97
CT Anatomy of the Heart 108
Patient and Occupational Dosimetry 124
Diagnostic Approaches to Patients with CAD 137
Patient Preparation and Stress Protocols for Cardiac PET and Integrated PET/ CT Imaging 138
PET and Integrated PET/ CT Myocardial Imaging Protocols and Quality Assurance 148
Myocardial Perfusion Imaging with PET 164
Quantifying Myocardial Perfusion for the Assessment of Preclinical CAD 173
Assessing Atherosclerotic Burden with CT 190
CT Coronary Angiography 204
Relative Merits of Coronary CTA and Coronary MRI 217
Integrated Assessment of Myocardial Perfusion and Coronary Angiography with PET/ CT 228
Diagnostic Approaches to the Patient with Heart Failure 237
PET Measurement of Myocardial Metabolism 238
Myocardial Viability Assessment with PET and PET/ CT 261
Myocardial Perfusion, Viability, and Functional Assessment with Contrast CT 281
Assessment of Myocardial Viability by Cardiac MRI 294
Comparison of Imaging Modalities in the Assessment of Myocardial Viability 306
Role of Imaging Cardiac Innervation and Receptors in Heart Failure 340
Emerging Role of Molecular Imaging 356
Evaluating High- Risk, Vulnerable Plaques with Integrated PET/ CT 357
Evaluating Vulnerable Atherosclerotic Plaque with MRI 370
Evaluating Gene and Cell Therapy 383
Imaging of Angiogenesis 404
Case Illustrations of Cardiac PETand Integrated PET/CT 422
Index 463

Erscheint lt. Verlag 5.12.2007
Zusatzinfo XVIII, 470 p. 254 illus., 97 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium 2. Studienabschnitt (Klinik) Anamnese / Körperliche Untersuchung
Schlagworte Computed • Computed tomography (CT) • Emission • PET/CT • positron • Positron Emission Tomography • Tomography
ISBN-10 0-387-38295-X / 038738295X
ISBN-13 978-0-387-38295-1 / 9780387382951
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