Cellular and Biomolecular Mechanics and Mechanobiology (eBook)

Preface.- Fundamental concepts .- Cytoskeletal mechanics and cellular mechanotransduction: A molecular perspective.- Forces during cell adhesion and spreading: implications for cellular homeostasis.- The physical mechanical processes that shape tissues in the early embryo.- Mechanobiology of primary cilia.- Mechanical response of living cells to contacting shear force.- Experimental methods.- Microfabricated devices for studying cellular biomechanics and mechanobiology.- Nanotechnology usages for cellular adhesion and traction forces.- Global and local effects in three-dimensional biological hydrogels.- Global and local effects in three-dimensional biological hydrogels.- Global and local effects in three-dimensional biological hydrogels.- Biomechanical characterization of single chondrocytes.- Mechanics of airway smooth muscle cells and the response to stretch.- Computational modeling.- Biomechanical modelling of cells in mechanoregulation.- Finite element modeling of cellular mechanics experiments.- Multiscale computation of cytoskeletal mechanics during blebbing.- Mechanobiology and finite element analysis of cellular injury during microbubble flows.- Mathematical modeling of cell adhesion in tissue engineering using continuum models.- Cell-material communication: mechanosensing modelling for design in tissue engineering.- Mechanobiology in cancer .- Structure-mechanical property changes in nucleus arising from breast cancer.- Adhesion and signaling of tumor cells to leukocytes and endothelium in cancer metastasis.- Cellular mechanics of acute leukemia and chemotherapy