Intraoperative Irradiation (eBook)
XVII, 529 Seiten
Humana Press (Verlag)
978-1-61779-015-7 (ISBN)
The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of eternal beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding.
This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-dose-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included.
Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.
The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of eternal beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding.This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-dose-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included.Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.
Preface 8
Contents 10
Contributors 14
General Rationale and Historical Perspective 20
Rationale and Historical Perspective of Intraoperative Irradiation 21
Biology of Large Dose per Fraction Irradiation 45
Methods and Techniques of Treatment 66
Intraoperative Electron Beam Irradiation: Physics and Techniques 67
HDR-IORT: Physics and Techniques 89
Electronic Brachytherapy/Low KV-IORT: Physics and Techniques 101
IORT with Electron-Beam, High-Dose-Rate Brachytherapy or Low- KV/ Electronic Brachytherapy: Methodological Comparisons 115
Normal Tissue Tolerance: IORT 132
Normal-Tissue Tolerance to IOERT, EBRT, or Both: Animal and Clinical Studies 133
Results of IORT Alone or Plus EBRT by Disease Site 153
Central Nervous System Tumors 154
Head and Neck Cancer 175
Breast Cancer 201
Lung Cancer 213
Gastric Cancer 235
Pancreas Cancer 261
Bile Duct and Gallbladder Cancer 284
Primary Colorectal Cancer 307
Recurrent Colorectal Cancer 333
Retroperitoneal Sarcomas 362
Extremity and Trunk Soft-Tissue Sarcomas 396
Bone Sarcomas 415
Gynecologic Malignancies 438
Genitourinary Cancer 465
Pediatric Malignancies 486
Conclusions and Future Possibilities 506
Conclusions and Future Possibilities: IORT 507
Index 523
| Erscheint lt. Verlag | 15.4.2011 |
|---|---|
| Reihe/Serie | Current Clinical Oncology | Current Clinical Oncology |
| Zusatzinfo | XVIII, 530 p. 70 illus., 45 illus. in color. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| ISBN-10 | 1-61779-015-X / 161779015X |
| ISBN-13 | 978-1-61779-015-7 / 9781617790157 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 14,2 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
