Pharmacotherapy of Diabetes: New Developments (eBook)
X, 289 Seiten
Springer US (Verlag)
978-0-387-69737-6 (ISBN)
Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types - 1 and 2 - of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine in general.
In the United States, 20.8 million children and adults, 7% of the population, have diabetes. While an estimated 14.6 million have been diagnosed, 6.2 million have yet to be diagnosed. Worldwide diabetes afflicts 150 million people. The World Health Organization estimates that by 2025 that figure will double. Diabetes is responsible for more deaths than AIDS and breast cancer, combined. It is a leading cause of blindness, kidney failure, amputations, heart complications and stroke.Treatment of Type 1 and Type diabetes has changed radically over the past few years. There are new opportunities for treating the key abnormality in diabetes, increased blood glucose, by effective agents such as new insulin preparations and oral agents.Increasing so-called non-glycemic intervention is of prime importance. Blood pressure lowering therapies, anti-cholesterol strategies, and specific treatment related to complications is becoming increasingly important.Pharmacotherapy of Diabetes is a unique, invaluable guide to all aspects of the pharmacological treatment of diabetes, covering basic concepts and an in-depth review of current and future therapies. This work provides an overview for the new changes in therapies that can be implemented in clinical practice and treatment of the diabetic patient.
Dedication 5
Aperitif 7
Contents 9
Contributors 12
Pharmacoepidemiology of Diabetes 16
New Definitions of Diabetes: Consequences 22
The Insulin Resistance Syndrome: Concept and Therapeutic Approaches 31
Medical Emergencies - Diabetic Ketoacidosis and Hyperosmolar Hyperglycaemia 43
Notes on the Use of Glucagon in Type 1 Diabetes 50
Insulin and New Insulin Analogues, Insulin Pumps and Inhaled Insulin in Type 1 Diabetes 51
Insulin and New Insulin Analogues with Focus on Type 2 Diabetes 62
The Place of Insulin Secretagogues in the Treatment of Type 2 Diabetes in the Twenty- First Century 75
Metformin - from Devil to Angel 85
The Glitazones, Lessons So Far 95
Antidiabetic Combination Therapy 106
The Incretin Modulators - Incretin Mimetics ( GLP- 1 Receptor Agonists) and Incretin Enhancers ( DPP- 4 Inhibitors) 117
The Role of Alpha-Glucosidase Inhibitors ( Acarbose) 148
Multifactorial Intervention in Type 2 Diabetes 158
Obesity and Pharmacological Treatment 170
Management of Diabetic Dyslipidaemia 175
Coronary Intervention and Ischemic Cardioprotection in Diabetic Patients 189
ACE-I and ARB and Blood Pressure Lowering, Including Effect on Renal Disease. Treatment of Advanced Diabetic Renal Disease 201
Aspirin and Antiplatelet Drugs in the Prevention of Cardiovascular Complications of Diabetes 211
Glycosylation Inhibitors, PKC Inhibitors and Related Interventions Against Complications 219
Diabetic Foot Ulcers 229
Pharmacotherapy in Diabetic Neuropathy 236
Pregnancy - Pharmacological Problems 247
Pharmacotherapy of Diabetic Retinopathy 253
Pharmacotherapy in Diabetic Sexual Dysfunction 259
A Bone Perspective 264
Achieving Guideline Control with New Pharmacotherapies: Albumin- Binding by Acylation of Insulin and GLP- 1 268
Pharmacotherapy of Diabetes 272
Index 277
| Erscheint lt. Verlag | 23.10.2007 |
|---|---|
| Zusatzinfo | X, 289 p. 45 illus. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Diabetologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Medizin / Pharmazie ► Pflege | |
| Schlagworte | AIDS • Diabetes • diabetes, pharmacotherapy, insulin • Insulin • insulin resistance |
| ISBN-10 | 0-387-69737-3 / 0387697373 |
| ISBN-13 | 978-0-387-69737-6 / 9780387697376 |
| Haben Sie eine Frage zum Produkt? |
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