Hormone Use and Abuse by Athletes (eBook)

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2010 | 2011
XII, 180 Seiten
Springer US (Verlag)
978-1-4419-7014-5 (ISBN)

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Physical activity exerts an important influence on the endocrine system, modulating synthesis and secretion of several hormones. Almost every organ and system in the body is affected by physical activity and exercise, mainly through the endocrine and neuroendocrine system. Mode, intensity, and duration of the exercise bout, age, gender and fitness level of the individual as well as environmental and psychological factors may affect the endocrine response to physical activity.

On the other hand, several hormones are able to influence physical performance and body composition. Thus, a bi-univocal interrelationship between exercise and hormones exists.

In this book new developments on metabolic and endocrine response to exercise are revised and introduce the 'hot topic' of hormonal doping in sports. In the past decades, hormone abuse has become a widespread habit among professional and - most of all and more frequently - recreational athletes. A substantial part of this volume is devoted to the effects of exogenous hormones on performance. Anabolic steroids, growth hormone and erythropoietin properties, use and misuse in sports are widely described. Specific methods to detect hormone abuse are presented and discussed.

The contributors to this volume are well-known experts and dedicated researchers in the fields of sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection.

The purpose of this volume is to provide all professionals involved in sports medicine and endocrinology a state-of-the-art overview of the complex interactions between physical activity and the endocrine system and to focus on hormone abuse in sports at competitive and recreational level highlighting its negative consequences for long-term health.


Physical activity exerts an important influence on the endocrine system, modulating synthesis and secretion of several hormones. Almost every organ and system in the body is affected by physical activity and exercise, mainly through the endocrine and neuroendocrine system. Mode, intensity, and duration of the exercise bout, age, gender and fitness level of the individual as well as environmental and psychological factors may affect the endocrine response to physical activity.On the other hand, several hormones are able to influence physical performance and body composition. Thus, a bi-univocal interrelationship between exercise and hormones exists.In this book new developments on metabolic and endocrine response to exercise are revised and introduce the "e;hot topic"e; of hormonal doping in sports. In the past decades, hormone abuse has become a widespread habit among professional and - most of all and more frequently - recreational athletes. A substantial part of this volume is devoted to the effects of exogenous hormones on performance. Anabolic steroids, growth hormone and erythropoietin properties, use and misuse in sports are widely described. Specific methods to detect hormone abuse are presented and discussed. The contributors to this volume are well-known experts and dedicated researchers in the fields of sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection.The purpose of this volume is to provide all professionals involved in sports medicine and endocrinology a state-of-the-art overview of the complex interactions between physical activity and the endocrine system and to focus on hormone abuse in sports at competitive and recreational level highlighting its negative consequences for long-term health.

Preface 6
Contents 8
Contributors 10
GH/IGF-I Axis in Exercise 14
Exercise, Training, and the Hypothalamo– Pituitary– Adrenal Axis 21
Thyroid Axis, Prolactin, and Exercise 28
Exercise, Training, and the Hypothalamic– Pituitary– Gonadal Axis in Men 36
Exercise and the Reproductive System in Women 42
Physical Exercise, Sports, and Diabetes 48
Motor Performance and Muscle Mass as a Function of Hormonal Responses to Exercise 54
Sports, Hormones, and Doping in Children and Adolescents 61
Androgen Abuse 72
Growth Hormone 97
Erythropoietin 107
Amino Acids and Nonhormonal Compounds for Doping in Athletes 118
The Assay of Endogenous and Exogenous Anabolic Androgenic Steroids 128
Problems with Growth Hormone Doping in Sports: Isoform Methods 138
Detection of Growth Hormone Doping in Sport Using Growth Hormone- Responsive Markers 145
Distinction Between Endogenous and Exogenous Erythropoietin: Marker Methods 157
Direct Methods for Distinction Between Endogenous and Exogenous Erythropoietin 168
Index 181

Erscheint lt. Verlag 28.10.2010
Reihe/Serie Endocrine Updates
Zusatzinfo XII, 180 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Sportmedizin
Schlagworte Anabolic Steroids • endocrine • Erythropoietin • exercise
ISBN-10 1-4419-7014-2 / 1441970142
ISBN-13 978-1-4419-7014-5 / 9781441970145
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