Hormone Therapy in Breast and Prostate Cancer (eBook)

An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer
V. Craig Jordan and Barrington J. A. Furr

Part I. Preclinical Antiestrogens

Antiestrogens and the Cell Cycle
Colin K. W. Watts, Owen W. J. Prall, Jason S. Carroll, Nicholas R. C. Wilcken, Eileen M. Rogan, Elizabeth A. Musgrove, and Robert L. Sutherland

Drug Resistance to Antiestrogens
Ruth M. O'Regan, Anait S. Levenson, Gale M. England, Kathy A. Yao, Henry D. Muenzner, Hiroyuki Takei, and V. Craig Jordan

Mechanisms of Liver Carcinogenesis by Antiestrogens
David H. Phillips

The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepatocarcinogenesis in the Rat
Yvonne P. Dragan and Henry C. Pitot

Preclinical Studies of Raloxifene and Related Compounds
Robin Fuchs-Young. Pure Antiestrogens, Alan E. Wakeling

Part II. Antiestrogens: Clinical

Tamoxifen for the Treatment of Breast Cancer
V. Craig Jordan

Clinical Utility of New Antiestrogens
Ruth M. O'Regan and William J. Gradishar

Breast Cancer Prevention with Antiestrogens
Monica Morrow and V. Craig Jordan

Part III. Inhibition of Estrogen Synthesis

Aromatase Inhibitors
Paul E. Goss and Caroline C. Reid

Clinical Utility of Aromatase Inhibitors
K. Shenton, Mitchell Dowsett, and Michael Dukes

LH-RH Agonists for the Treatment of Breast Cancer: Development and Current Status
Roger W. Blamey

Part IV. Androgen and Androgen Withdrawal

Molecular Action of Androgens
Shutsung Liao, Junichi Fukuchi, and Yung-Hsi Kao

Steroidal Antiandrogens
Fritz H. Schröder and Albert Radlmaier

Nonsteroidal Antiandrogens
Geert J. C. M. Kolvenbag and Barrington J. A. Furr

LH-RH Agonist Role in Prostate Cancer Management
Amir V. Kaisary

Part V. Perspective on Progress

Recent Progress in Breast Cancer Research
V. Craig Jordan and Barrington J. A. Furr