Allogeneic Stem Cell Transplantation (eBook)
XIX, 881 Seiten
Humana Press (Verlag)
978-1-59745-478-0 (ISBN)
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Preface 7
Contents 9
Contributors 13
Allogeneic Stem Cell Transplantation: The Last Century 20
Full Intensity and Reduced Intensity Allogeneic Transplantation in AML 29
Allogeneic Stem Cell Transplantation for Adult Acute Lymphoblastic Leukemia ( ALL) 46
Hematopoietic Progenitor Cell Transplantation for Treatment of Chronic Lymphocytic Leukemia 60
The Role of Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelogenous Leukemia Patients in the Era of Tyrosine Kinase Inhibitors 70
Allogeneic Transplantation for Hodgkin’s Lymphoma 92
Myeloablative Allogeneic Stem Cell Transplantation for Non- Hodgkin’s Lymphoma 106
Non-Hodgkin’s Lymphoma: Allogeneic Reduced Intensity Conditioning 126
The Role of Allogeneic Transplantation for Multiple Myeloma in Older Adults 143
Single Versus Tandem Autologous Hematopoietic Stem Cell Transplant in Multiple Myeloma 159
Treatment Strategies for Follicular Center Cell Non- Hodgkin’s Lymphoma 174
The Role of Transplantation in Favorable- Risk Acute Myeloid Leukemia 191
Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukaemia in Adults 207
Allogeneic Transplantation for Myelodysplastic Syndromes 217
Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia 232
Allogeneic Transplantation for the Treatment of Multiple Myeloma 274
Blood Vs. Marrow Allogeneic Stem Cell Transplantation 293
Hematopoietic Cell Transplantation from Partially HLA- Mismatched ( HLA- Haploidentical) Related Donors 310
Unrelated Donor Transplants 355
Update on Umbilical Cord Blood Transplantation 372
Selection of Cord Blood Unit(s) for Transplantation 384
Mobilization of Hematopoietic Cells Prior to Autologous or Allogeneic Transplantation 396
Natural Killer-Cell Based Treatment in Hematopoetic Stem Cell Transplantation 422
Cryopreservation of Allogeneic Stem Cell Products 435
Concepts and Controversies in the Use of Novel Preparative Regimens for Allogeneic Stem Cell Transplantation 448
Allogeneic Haematopoietic Stem Cell Transplantation and Natural Killer Cell Alloreactivity 466
Therapeutic Potential of Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation 484
Hematopoietic Stem Cell Transplantation for Thalassemia 498
Viral Infections in Hematopoietic Stem Cell Transplant Recipients 512
Fungal Infections 540
Immune Reconstitution and Implications for Immunotherapy Following Hematopoeitic Stem Cell Transplantation 552
Acute Graft Versus Host Disease: Prophylaxis 572
Chronic Graft-Versus-Host Disease 584
Post-transplant Lymphoproliferative Disorder 603
Psychological Care of Adult Allogeneic Transplant Patients 625
Second Allogeneic Transplantation: Outcomes and Indications 663
Minimal Residual Disease 673
Functional Assessment Tools and Co- morbidity Scoring in Hematopoietic Progenitor Cell Transplantation 692
Unique Thrombotic and Hemostatic Complications Associated with Allogeneic Hematopoietic Stem Cell Transplantation 700
How Much Isolation Is Enough for Allografts? 721
Monoclonal Antibodies in Allogeneic Hematopoietic Stem Cell Transplantation for Hematologic Malignancies 737
Treatment of Acute Graft-vs-Host Disease 751
The Importance of Non-Human Primate Models for Pre- clinical Studies in Hematopoiesis 770
In Vivo Models of Allogeneic Hematopoietic Stem Cell Transplantation 791
Dendritic Cells 808
Augmentation of Hematopoietic Stem Cell Transplantation with Anti- cancer Vaccines 856
Index 869
| Erscheint lt. Verlag | 2.3.2010 |
|---|---|
| Reihe/Serie | Contemporary Hematology |
| Zusatzinfo | XIX, 881 p. 66 illus., 10 illus. in color. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie |
| Medizinische Fachgebiete ► Innere Medizin ► Hämatologie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| Schlagworte | allogeneic graft technology • allogeneic stem cell • Allografts • Antibody • Blood • Cancer • Genome • Hematopoiesis • hematopoietic stem cell • hematopoietic stem cell transplantation • immune reconstitution • immunotherapy • Lymphoma • Stem Cells • stem cell transplantation • Transplantation |
| ISBN-10 | 1-59745-478-8 / 1597454788 |
| ISBN-13 | 978-1-59745-478-0 / 9781597454780 |
| Haben Sie eine Frage zum Produkt? |
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