Morphological and Cellular Aspects of Tail and Limb Regeneration in Lizards (eBook)

Abstract 6
Acknowledgements 7
Foreword 9
Contents 11
1: Regeneration in Reptiles and Its Position Among Vertebrates 12
Regeneration in the First Amniotes, the Reptiles 13
Significance of Tail Regeneration in Lizards: Zoological Background 18
Regeneration in Lizards: Growth Rates 25
Embryos of Lizards Fail To Regenerate Limbs and Tail 26
Histological and Histochemical Aspects of Tail Regeneration 28
Wound Healing and Blastema Formation 30
The Blastema Grows into a Cone 32
Tail Growth and Tissue Differentiation 37
Tail Scalation and Maturation 40
Histological Aspects of Limb Regeneration and Cicatrization 41
Single Tissue Regeneration in the Lizard Tail 46
Failure of Tail Regeneration and Cicatrization 58
2: Tail Regeneration: Ultrastructural and Cytological Aspects 61
Wound Healing to Blastema Formation 61
Tissue Differentiation 68
Epidermis 68
Blood Vessels, Fat, and Meninges 69
Muscles 75
Cartilage 77
Spinal Cord and Central Nerves 80
Spinal Ganglia and Peripheral Nerves 87
Growth Factors, Extracellular Matrix Proteins, and Keratins 89
Growth Factors 89
Extracellular Matrix Proteins 94
Intermediate Filament Proteins 95
3: Limb Regeneration: Ultrastructural and Cytological Aspects 99
Wound Healing and Blastema Formation 99
Scar Formation in the Limb as Compared with the Inducement of Tail Scarring 101
4: Conclusion and Perspectives: Implications for Human Regeneration 104
References 107