Diagnosis of Endometrial Biopsies and Curettings (eBook)

A Practical Approach
eBook Download: PDF
2005 | 2nd ed. 2005
X, 296 Seiten
Springer New York (Verlag)
978-0-387-26321-2 (ISBN)

Lese- und Medienproben

Diagnosis of Endometrial Biopsies and Curettings - Michael Mazur, Robert J. Kurman
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Derived from the authors' long-running course presented at the International Academy of Pathology, this second edition, now with color illustrations, continues the tradition of its predecessor as being the concise and complete diagnostic guide to the endometrial biopsy. The text is structured so as to present a logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory. Color illustrations show typical artifacts and distortion, and explain their impact on diagnostic interpretation. Each chapter includes a section summarizing the features that must be discussed in the final pathology report.


DIAGNOSIS OF ENDOMETRIAL BIOPSIES, Second Edition, revised and now with color illustrations, continues the tradition as being the most concise and complete diagnostic guide to the endometrial biopsy. A review from MODERN PATHOLOGY praises it as being "e;extremely useful for the practicing pathologist because it outlines criteria for diagnosis, helps in solving diagnostic diagnostic dilemmas, and clarifies controversial issues."e;The text is structured to present a logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory. Color illustrations show typical artifacts and distortion and explain their impact on diagnostic interpretation. Each chapter includes a section on "e;Clinical Queries and Reporting"e; that summarizes the features that must be discussed in the final pathology report. The authors are two prominent gynecologic pathologists, and this book is derived from their long-running Short Course presented at the International Academy of Pathology.

Preface to the Second Edition 5
Preface to the First Edition 7
Contents 9
Introduction 10
Indications for Biopsy 10
Clinical History and Biopsy Interpretation 11
Clinical Queries and Reporting 13
References 14
Normal Endometrium and Infertility Evaluation 16
General Considerations in Histologic Evaluation 17
Histologic Dating of the Normal, Cycling Endometrium 19
Pitfalls in Dating 30
Artifacts and Contaminants 32
Luteal Phase Defect and Abnormal Secretory Phase Patterns 35
Clinical Queries and Reporting 38
References 40
Pregnancy, Abortion, and Ectopic Pregnancy 43
Endometrial Glands and Stroma in Pregnancy 44
Trophoblast and Villi 52
Endometrium Associated with Ectopic Pregnancy 71
Clinical Queries and Reporting 72
References 73
Gestational Trophoblastic Disease 76
Hydatidiform Mole 76
Trophoblastic Neoplasms 90
References 103
Dysfunctional Uterine Bleeding 109
Morphologic Features of Glandular and Stromal Breakdown 109
Dysfunctional Uterine Bleeding 117
Progesterone-Related Bleeding 124
Clinical Queries and Reporting 128
References 128
Effects of Hormones 130
Estrogenic Hormones 131
Progestins and Oral Contraceptives 131
Combined Estrogen and Progestin as Replacement Therapy for Menopausal Women 140
Progestin-Like Effects with No Hormone Use 141
Effects of Other Hormones 142
Clinical Queries and Reporting 148
References 150
Endometritis 156
Nonspecific Endometritis 156
Specific Infections 163
Differential Diagnosis 167
Clinical Queries and Reporting 169
References 170
Polyps 172
Classification and Histologic Features 173
Differential Diagnosis 182
Clinical Queries and Reporting 184
References 185
Endometrial Hyperplasia, Endometrial Intraepithelial Carcinoma, and Epithelial Cytoplasmic Change 187
Terminology and Classification of Hyperplasia 188
Endometrial Hyperplasia 188
Endometrial Intraepithelial Carcinoma 202
Epithelial Cytoplasmic Change ( Metaplasia) 204
Clinical Queries and Reporting 213
References 214
Endometrial Carcinoma 217
Important Issues in Interpretation of Biopsies 218
Malignant Neoplasms— Classification, Grading, and Staging of the Tumor 225
Clinical Queries and Reporting 248
References 250
Other Tumors 258
Malignant Mixed Mesodermal Tumor ( Carcinosarcoma) 258
Mullerian Adenofibroma and Adenosarcoma 265
Stromal Tumors 269
Smooth Muscle Tumors 273
Rare Neoplasms 276
Other Lesions and Tumor- Like Conditions 278
References 279
Methods of Endometrial Evaluation 284
Endometrial Sampling Techniques 284
Noninvasive Methods of Endometrial Evaluation 285
Histologic Techniques 286
Frozen Section 287
Immunohistochemistry 288
References 290
Index 297

Erscheint lt. Verlag 27.12.2005
Zusatzinfo X, 296 p. 307 illus., 77 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium 2. Studienabschnitt (Klinik) Anamnese / Körperliche Untersuchung
Studium 2. Studienabschnitt (Klinik) Pathologie
Schlagworte biopsy • carcinoma • Differential Diagnosis • Endometrial Biopsy • Endometrium • fertility • hormones • Infertility • Pregnancy • tissue
ISBN-10 0-387-26321-7 / 0387263217
ISBN-13 978-0-387-26321-2 / 9780387263212
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