Hyperlipidemia Management for Primary Care (eBook)

An Evidence-Based Approach

Brian V. Reamy (Herausgeber)

eBook Download: PDF
2009 | 2008
XIV, 228 Seiten
Springer New York (Verlag)
978-0-387-76606-5 (ISBN)

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This book provides multifaceted strategies necessary to treat hyperlipidemia, as well as tips for incorporating techniques into clinical practice. In addition to discussing pharmacologic treatment, the book includes a review of popular diets and therapeutic foods, herbs, and vitamins. A section on evidence-based recommendations for treating special populations discusses approaches for elderly patients, women, elite athletes, and other populations with unique medical needs. Case studies illustrate the principles introduced in the book. The text is complete with screening tools for real world risk assessment.


One of the possible bene?ts of 30 years of medical practice is the ability to develop some sense of perspectivewith regardto majortransitionsin medicine. Manyphy- cians who graduated from medical school in the mid- to late 1970s may recall fe- ing less than comfortable about counseling patients regarding lifestyle modi?cation and heart disease risk. A total cholesterol of 250 mg% at that time was considered within normal limits. The best information on the causation of heart disease came from epidemiologic data showing associations between increased consumption of dairy products and fat in the industrialized countries of northern Europe and Am- ica, and a corresponding increase in morbidity and mortality from heart disease as compared to other countries that were less well developed or as compared to Mediterranean countries, where there was a different type of diet lower in saturated fats and cholesterol. Treatment options in those days were based more on anecdotal information and observation than on evidence. The idea that coronary artery disease was an in?- matory problem in which the main culprit was oxidized LDL and the idea that heart disease risk could be managed had not yet made the transition to clinical pr- tice. This attitude all changed as information from the largest and longest running prospective epidemiologic study on heart disease-the Framingham Study-began publishing data on causality and risk factors.

OVERVIEW OF EVIDENCE SUPPORTING TREATMENT OF HYPERLIPIDEMIA. Pre-statin trials. Primary prevention statin trials. Secondary prevention statin trials. Other trials. Normal Lipid Values. NCEP/ATP-III GUIDELINES. Review of ATP-III for treatment of hyperlipidemia. Review of 2004 ATP-III update. Review of ATP-IV. LIFESTYLE CHANGES AND NON-DRUG TREATMENT. Weight loss and other diets--benefits and risks. Therapeutic foods. Exercise interventions--benefits and risks. DRUG TREATMENT. General principles of drug treatment of hyperlipidemia. Agents (action, dosing, side effects, unique uses). Drug interactions. Drug intolerance and severe side effects. Drugs of the future. SPECIAL POPULATIONS AND SITUATIONS. Elderly patients .-Patients with multiple medical problems. Women. Adults younger than 35 years of age. Children. Elite athletes. Native Americans. Immigrants. Family issues. Community issues and population health concerns. OTHER ISSUES IN PREVENTION OF CARDIOVASCULAR DISEASE. Aspirin prophylaxis. Novel screening tools for risk assessment. PRACTICAL APPROACH TO THE PATIENT WITH HYPERLIPIDEMIA. Treatment algorithms. Visit and serum testing frequency. Compliance and motivational tools. Referral guidelines for refractory hyperlipidemia. CASE STUDIES. The well elderly patient. The well young patient. The diabetic. The patient with intermediate risk. The unreachable goal. Kids. Normal cholesterol, but high TG and low HDL. Can't use statins. Metabolic syndrome. FUTURE DIRECTIONS. How low do you go? PPARs and prevention of metabolic syndrome. Integrative treatment (diet + exercise + drugs).

Erscheint lt. Verlag 1.3.2009
Zusatzinfo XIV, 228 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitswesen
Medizin / Pharmazie Medizinische Fachgebiete Allgemeinmedizin
Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Medizin / Pharmazie Medizinische Fachgebiete Notfallmedizin
Medizin / Pharmazie Medizinische Fachgebiete Sportmedizin
Schlagworte Cardiovascular • Care • Cholesterol • heart • Heart disease • high-density lipoprotein (HDL) • Lipids • Management • Obesity • prevention • Primary Care • Treatment • vascular disease
ISBN-10 0-387-76606-5 / 0387766065
ISBN-13 978-0-387-76606-5 / 9780387766065
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