Allergy Frontiers:Classification and Pathomechanisms (eBook)
XXII, 606 Seiten
Springer Tokyo (Verlag)
978-4-431-88315-9 (ISBN)
When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as "e;Exosomes, naturally occurring minimal antigen presenting units"e; and "e;Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene."e; The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic u- ally confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease.
Foreword 5
Preface 11
Contents 13
Contributors 17
Classification and Pathomechanisms 23
Basic Aspects of Allergy and Hypersensitivity Reactions 24
Pathogen Recognition and New Insights into Innate Immunity 39
New Nomenclature and Clinical Aspects of Allergic Diseases 51
IgE and the High-Affinity Receptor, FceRI: The IgE–CD23 Interaction 63
Superantigens and Allergic Disease 78
Immune Complexes: Normal Physiology and Role in Disease 97
What Is New About Eosinophil Activation in Asthma and Allergic Disease 113
Mast Cell and Basophils: Interaction with IgE and Responses to Toll like Receptor Activators 130
T Cells in Allergic Disease 151
Role of NKT Cells in the Regulation of Ongoing Type 2 Immune Response 166
CD8+ T Cells Play a Key Role in the Development of Allergic Lung Inflammation 181
Neutrophils and Their Mediators in Asthma and Allergic Disease 193
Dendritic Cells, Macrophages and Monocytes in Allergic Disease 208
Function of Dendritic Cell Subsets in Allergic Disease 221
Epithelial Cell-Mesenchymal Interaction, Epithelial-Leukocyte Interaction and Epithelial Immune-Response Genes in Allergic Disease 243
Role of Epidermal Growth Factor Receptor Cascade in Airway Epithelial Regulation of Mucus Production 261
Epithelial Cell Innate Responses to Rhinovirus Infection 278
The Role of Platelets in Allergy 296
Expression and Function of Siglec-8 in Human Eosinophils, Basophils, and Mast Cells1 308
Effects of Nitric Oxide on Mast Cells: Production, Functions, and Mechanisms of Action 325
Histamine and Its Receptors 338
Adenosine: Its Contribution to Our Understanding in Airway Inflammation 366
Airway Smooth Muscle Dysfunction in Asthma 386
Genetic Variation in Cytokines, Asthma, and Atopy: The Role of IL-4/IL-13 Pathway Polymorphisms 410
Allergy and the Bone Marrow: Transmigration Pathways of Hemopoietic Progenitor Cells from the Bone Marrow 429
Hemopoietic Mechanisms in Allergic Rhinitis and Asthma 441
Allergy and the Nervous System 462
Neuroanatomy of the Airways 463
Biology of Neurotrophins, Neuropeptides, and Muscarinic Receptors in Asthma 475
Neural Regulation of the Immune Response 498
Neuroregulation of Mucosal Vasculature 520
Allergy and Mucosal Immunology 532
Mucosal Immunity: from Allergy to Coeliac Disease 533
Mucosa-Associated Lymphoid Tissue and Dynamics of Lymphoid Cells in the Five Different Compartments in Allergic Diseases 566
Index 605
Erscheint lt. Verlag | 13.3.2009 |
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Reihe/Serie | Allergy Frontiers | Allergy Frontiers |
Zusatzinfo | XXII, 606 p. |
Verlagsort | Tokyo |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Innere Medizin | |
Schlagworte | allergy • Antigen • Asthma • Cytokine • Diseases • immunology • Infection • inflammation • Innate Immunity • Macrophages • Muscle • Physiology |
ISBN-10 | 4-431-88315-0 / 4431883150 |
ISBN-13 | 978-4-431-88315-9 / 9784431883159 |
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