Hyperthermia In Cancer Treatment: A Primer (eBook)

CONTENTS 5
EDITORS 10
CONTRIBUTORS 10
PREFACE 14
INTRODUCTION 16
Physical Aspects of Hyperthermia 22
Hyperthermia, Physics, Vector Potential, Electromagnetic Heating: A Primer 23
Thermometry: Clinical Aspects and Perspectives 39
Physical Backround and Technical Realizations of Hyperthermia 47
Thermotherapy and Nanomedicine: Between Vision and Reality 80
Biological Aspects of Hyperthemia 84
Influence of Tumor Microenvironment on Thermoresponse: Biologic and Clinical Implications 85
Hyperthermia and Angiogenesis: Results and Perspectives 110
Vascular Effects of Localized Hyperthermia 117
On the Biochemical Basis of Tumour Damage by Hyperthermia 128
Results of Hyperthermia Alone or with Radiation Therapy and/or Chemotherapy 137
Thermo-Chemo-Radiotherapy Association: Biological Rationale, Preliminary Observations on Its Use on Malignant Brain Tumors 146
A Step Deep on Hyperthermia, Hypoxia and Chemotherapy Interactions 174
Clinical Aspects of Hyperthermia 182
Locoregional Hyperthermia 183
Hyperthermia and Radiotherapy in the Management of Prostate Cancer 199
Tumor Ablation Using Radiofrequency Energy: Technical Methods and Application on Liver Tumors 206
Cytoreduction, Peritonectomy and Hyperthermic Antiblastic Peritoneal Perfusion for die Treatment of Peritoneal Carcinomatosis 215
Hyperthermic Isolated Limb Perfusion 224
Intracavitary Hyperthermic Perfusion 234
Whole Body Hyperthermia at 43.5-44''C: Dream or Reality? 243
Extreme Whole-Body Hyperthermia with Water-Filtered Infrared-A Radiation 253
Effects of Local and Whole Body Hyperthermia on Immunity 263
Fever, Pyrogens and Cancer 292
Future Perspectives of Interstitial and Perfusional Hyperthermia 354
Addendum: Radiofrequency Thermal Ablation in the Treatment of Lung Malignancies 368
Index 377