Somatic Cell Genetics

Pathway Mutants in Mammalian Cells and their Contribution to the Analysis of Drug Resistance.- Isolation and Analysis of Chinese Hamster Cells Carrying Forward and Reverse Mutations in the Hypoxanthine-Guanine Phosphoribosyltransferase Locus.- Towards Mapping Genes to Chromosomes Using Two Dimensional Gel Electrophoresis of Proteins and Somatic Cell Hybridization. Preliminary Studies.- The Use of Mouse-Human and Human-Human Hybridomas in Human Genetics and Immunology.- Expression of Liver Mono-Oxygenase Functions Induced by Xenobiotics.- Gene Mapping and Gene Transfer in Mammalian Cells.- Dihydrofolate Reductase Gene Amplification, Altered Dihydrofolate Reductase, and Methotrexate Resistance in Cultured 3T6 Cells Associated with Unstable Amplification of an Altered Dihydrofolate Reductase Gene.- Transformation and Expression of TK Sequences.- Genetic Variants of Cultured Animal Cells.- Cell Hybridization: A Tool for the Study of Cell Differentiation.- Use of Somatic Cell Hybridization and DNA-Mediated Gene Transfer for Characterization of Neoplastic Transformation.- Analysis of Cell Surface Antigens with Monoclonal Antibodies.- List of Contributors.