Transporters as Targets for Drugs -

Transporters as Targets for Drugs

Susan Napier, Matilda Bingham (Herausgeber)

Buch | Softcover
XIV, 254 Seiten
2010 | 1. Softcover reprint of hardcover 1st ed. 2009
Springer Berlin (Verlag)
978-3-642-09969-4 (ISBN)
266,43 inkl. MwSt
With contributions by numerous experts

M. Bingham - S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte - A.W. Ravna - G. Sager - S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock - M.D. Andrews - A.D. Brown - P.V Fish - A. Stobie - F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIs

A. Hauck Newman - J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter

Z. Chen - J. Yang - P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni - J. Sörensen - H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges - S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc

R. Gilfillan - J. Kerr G. - Walker - G. Wishart: Glycine Transporters and Their Inhibitors

Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.

Erscheint lt. Verlag 28.10.2010
Reihe/Serie Topics in Medicinal Chemistry
Zusatzinfo XIV, 254 p. 109 illus., 11 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 407 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Organische Chemie
Schlagworte Cocaine • dopamine • medicinal chemistry • Molecular Chemistry • Organic Chemistry • Pharmaceutical Chemistry • Pharmacy
ISBN-10 3-642-09969-6 / 3642099696
ISBN-13 978-3-642-09969-4 / 9783642099694
Zustand Neuware
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