Tumor Targeting in Cancer Therapy

I. A Review.- 1 The Current Status of Tumor Targeting: A Review.- 2 Clinical Applications of Targeted Therapeutics.- II. Targeting Tumors with Drug Antibody Conjugates.- 3 Targeting the CD22 Receptor with RNA Damaging Agents.- 4 The Development of Liposomes for Enhanced Delivery of Chemotherapeutics to Tumors.- 5 Overcoming Multiple Drug Resistance with Anti-Pgn Carrier.- 6 Targeting with Transferrin.- 7 Synthesis and Evaluation of Paclitaxel Immunoconjugate with Antitumor Activity In Vitro.- 8 The Use of Drug-Monoclonal Antibody Conjugates for the Treatment of Cancer.- III. Targeting Tumors with Antibodies.- 9 Targeting Vascular Endothelium with Antibodies.- 10 Targeting B-Cell Non-Hodgkin’s Lymphoma with Monoclonal Antibodies.- 11 From Bench to Bedside: Development of Rituximab (Rituxan®), A Monoclonal Antibody for the Therapy of Non-Hodgkin’s Lymphoma.- 12 Mylotarg: The First Antibody-Targeted Chemotherapy Agent..- IV. Targeting Tumors with Radioimmunoconjugates.- 13 188Rhenium-Labeled Trisuccin-?CH2HuCC49 as a Radioimmunotherapy Model in Nude Mice.- V. Targeting Tumors with Immunotoxins.- 14 General Approach for Targeting Toxins.- 15 Antibody-Toxin Conjugates: Chemistry of Coupling and Purification.- 16 Shiga-Like Toxins as Targeted Anticancer Agents.- VI. Targeting Tumors with Antibody-Enzyme Conjugates (ADEPT).- 17 Antibody-Directed Enzyme Prodrug Therapy with Carboxypeptidase G2: Clinical Studies.- VII. Photodynamic Therapy.- 18 Photodynamic Therapy: Targeting Cancer Cells with Photosensitizer-Bioconjugates.- 19 Tumor Targeting Using PEG-m-THPC for Photodynamic Therapy in a Rat Ovarian-Cancer Model.- VIII. Targeting Tumors with Magnetic Drugs.- 20 Targeting Tumors with Magnetic Drugs.- IX. Principles and Techniques in Targeting.- 21 Internalization ofAntibodies.- 22 Bioconjugation and Biodistribution.- 23 Principles of Antitumor Targeting of Cytotoxic Drugs.- 24 Targeting by Antibody or Ligand: Which Is Better?.