Physiology and Pathophysiology of the Islets of Langerhans

I. Preface.- II. Stimulus Secretion Coupling: Are K(ATP) Channels Enough?.- III. Modulation of Islet Release.- IV. ?-Cell Metabolism and [Ca2+]i.- V. ?-Cell Heterogeneity: Building an Homogeneous Response from an Heterogeneous Population.- VI. IDDM (Insulin Dependent Diabetes Mellitus): What Went Wrong? Mechanisms of ?-Cell Destruction and Defense.- VII. Pathophysiology of the NIDDM.- VIII. Islet Growth, Regeneration, and Transplantation.