Gastrointestinal Bleeding

Joseph Sung, MD, PhD is Professor of Medicine and Director of Institute of Digestive Disease at the Chinese University of Hong Kong. His major research interest is on endoscopic and pharmacologic therapy of peptic ulcer bleeding, screening and early diagnosis of digestive disease cancers. He has published over 450 full scientific articles and serves as Associate Editor for GIE. Ernest Kuipers, MD, PhD is Professor of Medicine and Head of Departments of Gastroenterology & Hepatology, and Internal Medicine at Erasmus MC Hospital in the Netherlands. His main interest of research includes Helicobacter pylori infection and its relationship with gastritis and gastric cancer, gastro-esophageal reflux disease and endoscopic technology. He has published over 320 publications and serves as Associate Editor for Gut. Alan Barkun, MD is Professor of Medicine and Chief of Gastroenterology at Montreal General Hospital, McGill University, Canada. He is an endoscopist as well as epidemiologist with major interest in clinical trial design, consensus and guideline development in gastrointestinal bleeding. Dr. Barkun has published over 170 full scientific articles and serves in the research committee of ASGE.

List of Contributors, vii Part I: General Approach to Upper and Lower GI Bleeding

1 Gastrointestinal Bleeding: Presentation, Differential Diagnosis and Epidemiology, 1
Joseph Sung

2 Gastrointestinal Bleeding: Resuscitation, ICU Care and Risk Stratification, 15
Joseph Sung

3 Gastrointestinal Bleeding: Antiplatelets and Anticoagulants, 29
Joseph Sung

Part II: Peptic Ulcer Bleeding

4 Peptic Ulcer Bleeding: Endoscopic Diagnosis, Endoscopic Therapy and Pharmacotherapy, 41
I. Lisanne Holster, Caroline M. den Hoed & Ernst J. Kuipers

5 Peptic Ulcer Bleeding: Surgery and Radiology, 78
Irene M. Mulder, Ernst J. Kuipers & Johan F. Lange

Part III: Variceal Bleeding

6 Variceal Bleeding: Endoscopic Diagnosis, Endoscopic Therapy and Pharmacotherapy, 97
Dennis M. Jensen, Thomas O.G. Kovacs & Disaya Chavalitdhamrong

7 Variceal Bleeding: Surgery and Radiology, 119
Dennis M. Jensen, Thomas O.G. Kovacs & Disaya Chavalitdhamrong

Part IV: Other Causes of Upper GI Bleeding

8 Other Causes of Upper Gastrointestinal Bleeding, 135
I. Lisanne Holster & Ernst J. Kuipers

Part V: Lower GI Bleeding

9 Lower GI Bleeding: Endoscopic, Radiological and Surgical Diagnosis and Management, 177
Ana Ignjatovic, John T. Jenkins & Brian P. Saunders

Part VI: Small Bowel Bleeding

10 Small Bowel Bleeding, 212
Daniela E. Serban & Ernest G. Seidman

Part VII: GI Bleeding of Unknown Origin

11 Gastrointestinal Bleeding of Unknown Origing, 247
Larry H. Lai, Aric J. Hui & James Y.W. Lau

Part VIII: Methodology and Guidelines

12 Design of Clinical Trials in Gastrointestinal Bleeding, 280
Vipul Jairath & Alan N. Barkun

13 Guidelines and Consensus on Gastrointestinal Bleeding, 304
Alan N. Barkun

Index, 325