Vaccines for the Prevention of Cervical Cancer

Peter Stern, Henry Kitchener (Herausgeber)

Buch | Softcover

176 Seiten

2009 | Revised edition
Oxford University Press (Verlag)
978-0-19-958863-3 (ISBN)

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Cervical cancer is the second most common form of cancer found in women and is responsible for more than a quarter of a million deaths worldwide each year. With approximately 70% of cervical cancers now known to be caused by two oncogenic types of the human papillomavirus (HPV), there is great interest surrounding the approval of the vaccine for clinical use. Despite this, many questions remain about how the new vaccines should be implemented and how cervical cancer screening will change following vaccination.

This practical pocketbook provides an overview of the role of HPV in the pathophysiology of cervical cancer and its current screening and management, the principles of immune control of HPV infection in cervical cancer, and the challenges of implementing HPV vaccines and future developments. This revised edition includes updated trial data in the chapter on prophylactic HPV vaccination: current status.

Peter L. Stern is Professor of Immunology, Patterson Institute of Cancer Research, Christie Hospital NHS Trust, University of Manchester, Manchester, UK Henry C. Kitchener is Professor of Gynacological Oncology at St. Mary's Hospital, University of Manchester, manchester, UK

1. The UK cervical screening programme ; 2. Management of cervical intraepithelial neoplasia (CIN) ; 3. Role of HPV in cervical carcinogenesis ; 4. HPV and genital cancer: the essential epidemiology ; 5. The role of HPV testing in cervical screening ; 6. Natural immune control of HPV infection ; 7. Prophylactic HPV vaccines: pre-clinical and proof of principle studies ; 8. Prophylactic HPV vaccination: current status ; 9. Introduction of HPV prophylactic vaccination ; 10. HPV vaccination in the developing world ; 11. Screening post vaccination ; 12. Second-generation HPV prophylactic vaccines ; 13. Therapeutic HPV vaccines ; 14. Conclusion

Erscheint lt. Verlag	19.11.2009
Reihe/Serie	Oxford Oncology Library
Verlagsort	Oxford
Sprache	englisch
Maße	100 x 180 mm
Gewicht	149 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
ISBN-10	0-19-958863-5 / 0199588635
ISBN-13	978-0-19-958863-3 / 9780199588633
Zustand	Neuware