The Enigma of Slow Viruses
Springer Wien (Verlag)
978-3-211-82427-6 (ISBN)
1. Introduction: subacute spongiform virus encephalopathies from the perspective of a neuroscientist.- 2. The molecular biology of the slow viruses.- 2.1. The search for the virus-specific nucleic acid.- 2.2. The prion protein.- 2.3. The structure of the gene encoding PrP 33-35 (Prn-p) in different species.- 2.4. The models of slow viruses.- 3. The pathogenesis of slow virus infection.- 3.1. The general sequence of the pathogenetic events.- 3.2. The role of the spleen.- 3.3. The role of the spleen in neuroinvasion.- 3.4. The role of viremia.- 3.5. The role of macrophages in scrapie infection.- 3.6. The neural spread of infectivity from the spleen to the central nervous system.- 3.7. The neural spread of infectivity within the central nervous system.- 3.8. Biochemistry and histochemistry of slow virus infections.- 4. Neuropathology of slow virus diseases Ill.- 4.1. Natural scrapie.- 4.2. Kuru.- 4.3. Creutzfeldt-Jakob disease (CJD).- 4.4. Elements of neuropathology of slow virus disorders.- 5. Final conclusions.- Addendum.- References.
Erscheint lt. Verlag | 5.4.1993 |
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Reihe/Serie | Archives of Virology. Supplementa |
Zusatzinfo | XVI, 277 p. |
Verlagsort | Vienna |
Sprache | englisch |
Maße | 210 x 279 mm |
Gewicht | 858 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Schlagworte | Archives of Virology; Supplementum 6 • biochemistry • brain • Diseases • Gene • Genetics • immunology • Infection • Infections • Molecular Biology • nervous system • neurochemistry • Neuropathology • pathogenesis • Pathology • Virus • Viruskrankheiten |
ISBN-10 | 3-211-82427-8 / 3211824278 |
ISBN-13 | 978-3-211-82427-6 / 9783211824276 |
Zustand | Neuware |
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