Nephrology

I.- Volume I.- Normal Structure and Function.- Transport Processes and Epithelia.- Determinants of Growth, Form, and Function in Epithelia.- Basolateral Membrane Properties of Sodium-absorbing Epithelia.- Sodium-Glucose Cotransport Mechanisms.- Cell Volume Regulation in Epithelia.- Role of Cytosolic Calcium in Vasopressin-sensitive Epithelia.- Role of Cytosolic Calcium in Renal Tubular Transport.- Sodium Phosphate Cotransport: Studies with Vesicles and LLC-PK1 Cells.- Regulation of the Na+/H+ Antiporter in Cells of the Proximal Tubule.- Renal Nerves.- Functions of the Renal Nerves.- Renal Circulation.- Organization of the Medullary Circulation: Functional Implications.- Pathophysiology of the Medullary Circulation.- Intrarenal Control of Medullary Blood Flow and the Urinary Concentrating Mechanism.- Glomerular Filtration.- Intrarenal Control of Glomerular Filtration: Cellular Mechanisms of Tubuloglomerular Feedback.- Regulatory Role of the Tubuloglomerular Feedback Mechanism.- Influence of Renal Nerves on the Glomerular Microcirculation.- Structure and Transport Along the Nephron.- Hydrogen Ion Transport Along the Nephron.- Proximal Tubule Transport.- Transport Properties of the Pars Recta.- Function of the Thin Limb of Henle’s Loop.- Regulation of Sodium Chloride Transport by the Loop of Henle.- Sodium Chloride Reabsorption in the Thick Ascending Limb of the Loop of Henle.- Structural Heterogeneity of the Distal Nephron.- Control of Acid and Electrolyte Excretion.- Acidification Mechanisms.- Atrial Natriuretic Factor.- Regulation of Potassium Excretion.- Renal Metabolism, Prostaglandins, and Renin.- Contemporary Issues in Renal Metabolism.- Biochemistry of Renal Prostaglandins.- From Molecular Biology to Antihypertensive Drugs: Current Research on Renin Inhibitors.- Inactive Renin.- The Renin Gene: Structure and Processing of Renin.- Intracellular Actions of Renin.- The Endocrine System and the Kidney.- Similarity of the Effects of Antidiuretic Hormone, Parathyroid Hormone, Calcitonin, and Glucagon on Rat Kidney.- Brush Border and Basal-Lateral Membranes in the Action of Thyroid Hormone on the Proximal Tubule.- Binding of Aldosterone and Corticosterone Along the Nephron and Effects on Na-K-ATPase.- Localization of Aldosterone Receptors Along the Nephron.- Mechanism of Action of Aldosterone: Effects on Sodium, Potassium, and Hydrogen Transport.- Mechanism of Action of Aldosterone: Role of Na-K-ATPase.- Renal Actions by Which Vasopressin May Aid the Concentration of Urine.- Cellular Modes of Action of Vasopressin.- Specificity of Agonistic and Antagonistic Analogues of Vasopressin.- Cardiovascular Effects of Vasopressin.- Alterations of Extracellular Fluid Volume.- Edema.- Newer Concepts of Starling Equilibrium at the Capillary Level in the Production of Edema.- Pathogenesis of Edema in Cirrhosis.- Renal Handling of Sodium in Hepatic Diseases Other than Cirrhosis.- Primary Renal Sodium Retention in the Nephrotic Syndrome.- Causes and Mechanisms of Renal Injury.- Immunologic Mechanisms in Renal Disease.- Cellular and Humoral Mediators of Renal Injury.- Mechanisms of Immune Complex Formation and Deposition in Glomeruli.- Characteristics of Circulating Immune Complexes That Deposit in Renal Glomeruli.- Etiologic Factors in Immunologically Mediated Glomerulonephritis.- Role of Antigen and Antibody Charge in Immune Complex Disease.- Pathogenic Antigen of Heymann Nephritis (gp330): Identification, Isolation, and Localization.- Monoclonal Antibodies as Probes of Normal and Abnormal Renal Structure.- Role of Proteoglycans in Glomerular Function and Pathology.- Glomerular Arachidonic Acid Metabolism in Nephrotoxic Serum Nephritis.- Effects of Dexamethasone on Cultured Mesangial Cell Function During Phagocytosis.- Diseases of the Kidneys.- Primary Glomerular Diseases.- Poststreptococcal Glomerulonephritis.- Minimal Change Disease, Mesangial Proliferative Glomerulonephritis and Focal Sclerosis: Individual Entities or a Spectrum of Disease?.- Pathogenetic Mechanisms of IgA Nephropathy from Studies of Experimental Models.- Immunologic Aspects of IgA Nephropathy in Humans.- Clinicopathologic Correlations in IgA Nephropathy.- Natural History and Treatment of Idiopathic IgA Nephropathy.- Acute Renal Failure.- Principles of Acute Renal Failure.- Pathology of Acute Renal Failure.- Experimental Acute Renal Failure: Pathophysiology and Methods of Protection.- Control of Renal Regeneration After Acute Tubular Necrosis.- Contribution of Proteases to Hypercatabolism in Acute Renal Failure.- Cellular Mechanisms of Protection in Nephrotoxic and Ischemic Acute Renal Failure.- Clonidine, Propranolol, and the Prevention of Acute Renal Failure.- The Role of Calcium Channel Blockers.- Adenine Nucleotides in the Prevention of Ischemic Acute Renal Failure.- Nephrotoxicity.- Mechanisms of Drug Nephrotoxicity.- Nephrotoxicity of Nonsteroidal Anti-Inflammatory Drugs.- Renal Damage Induced by Radiologic Contrast Media.- Antibiotic-Induced Nephrotoxicity.- Nephrotoxicity Caused by Cancer Chemotherapy.- Volume II.- The Kidney in Systemic Disease.- Renal Involvement in Multiple Myeloma.- Pathology of Light Chain Nephropathies.- Glomerular Lesions in Lymphomas and Leukemias.- Sickle Cell Nephropathy.- Tubular Defects.- Isolated Tubular Defects.- Obstructive Uropathy and Urinary Reflux.- Pathophysiology of Obstructive Uropathy.- Vesicoureteral Reflux and Renal Damage.- Renal Scars and Vesicoureteric Reflux: Pathology and Pathogenesis of Segmental Atrophy.- Natural History and Treatment of Reflux Nephropathy.- Urolithiasis.- Pathogenesis of Calcium Renal Stones.- Physicochemical Factors in Calcium Oxalate Urolithiasis.- Use of Thiazide Diuretics in Calcium Oxalate Nephrolithiasis.- Agents Other Than Thiazide Diuretics in the Treatment of Calcium Oxalate Nephrolithiasis.- Urinary Inhibitors of Calcium Oxalate Crystallization.- Kidney Diseases in the Tropics.- Nephrotic Syndrome in Tropical Africa: Glomerulonephritis in Zimbabwe.- Renal Involvement in Leptospirosis.- Diabetes Mellitus and the Kidney.- Clinical and Renal Functional Studies of Diabetic Nephropathy in Humans.- Altered Glomerular Metabolism in Diabetes Mellitus.- Pathophysiology of Proteinuria in Diabetic Nephropathy.- Early Markers of Diabetic Nephropathy: A Road to Prevention.- Can the Insulin-Dependent Diabetic Patient Be Managed Without Kidney Biopsy?.- Pathogenesis as a Determinant of Therapy in Diabetic Nephropathy.- Hypertension.- Hypertension: Current Concepts of Mechanism and Management.- Effect of Dietary Fish Oils on Eicosanoid Formation in Platelets, Neutrophils, and the Cardiovascular-Renal System.- Calcium, Phosphate, and Parathyroid Hormone in Blood Pressure Regulation.- Role of Sodium and Other Dietary Factors in Hypertension.- Hypertension in the Elderly.- Mechanisms of Action and Use of Newer Antihypertensive Agents.- An Analysis for and Against Treatment of Mild Hypertension.- Phosphate Depletion.- Clinical Spectrum of Phosphate Depletion and Its Effects on Urinary Acidification.- Effect of Phosphate Depletion on Renal Tubular Transport.- Phosphate Depletion and Renal Cell Metabolism.- Mechanisms of Myocardial Injury in Phosphate Depletion.- Pathogenesis and Consequences of Chronic Renal Failure.- Mechanisms of Progression of Renal Disease.- Pathogenesis of Uremia.- Endocrine and Metabolic Abnormalities.- Regulation of Parathyroid Gland Activity.- The Status of Parathyroid Hormone Measurements in Humans.- Parathyroid Hormone: Alterations in Chronic Renal Failure.- Vitamin D and Kidney Disease.- Endocrine and Metabolic Abnormalities in Acute Renal Failure.- Insulin, Glucose, Amino Acid, and Lipid Metabolism in Chronic Renal Insufficiency.- Endocrine and Metabolic Abnormalities in the Nephrotic Syndrome: Calcium and Carbohydrate Metabolism.- Osteodystrophy.- Renal Osteodystrophy: General Concepts and Current Issues.- Prevalence of Various Types of Bone Disease in Dialysis Patients.- Role of Aluminum Accumulation in Renal Osteodystrophy.- Treatment of Renal Osteodystrophy in Chronic Renal Failure.- Hematopoietic System.- Prostanoid-Related Platelet Abnormalities in Renal Disease.- Gastrointestinal.- Intestinal Transport of Minerals in Renal Failure.- Evaluation and Management of Kidney Diseases and Renal Failure.- Microscopic and Biochemical Analysis of the Urine in the Evaluation of Kidney Disease.- Newer Imaging Techniques in Nephrology.- Are Randomized Trials in Kidney Disease Worthwhile?.- Infections.- Current Concepts in the Management of Urinary Tract Infections.- Treatment of Glomerular Diseases.- Treatment of Glomerulonephritis Based on Knowledge of Its Pathogenesis.- Use of Pulse Methylprednisolone in Primary and Multisystem Glomerular Diseases.- Plasma Exchange for Glomerular Disease.- Treatment of Glomerular Disease with Anticoagulant, Antiplatelet, and Nonsteroidal Anti-inflammatory Agents.- Nutrition in Renal Failure.- Causes of Catabolism and Wasting in Acute or Chronic Renal Failure.- Influence of Nutritional Therapy on Progression of Renal Insufficiency.- Dialysis.- Advantages and Disadvantages of Current Dialysis Techniques.- Vascular Access for Hemodialysis.- Anatomic and Physiologic Aspects of Peritoneal Dialysis.- Efficacy and Adequacy of Continuous Ambulatory Peritoneal Dialysis.- Continuous Ambulatory Peritoneal Dialysis in Diabetic Patients.- Long-Term Metabolic Consequences of Continuous Ambulatory Peritoneal Dialysis.- Transplantation.- Renal Transplantation: Current Status.- Endocrine and Metabolic Dysfunctions Following Kidney Transplantation.- Cyclosporine in Renal Transplantation.- The Transfusion Effect in Renal Allograft Recipients.- Antilymphocyte Globulin and Monoclonal Antibodies: Present Status as Therapy.- Total Lymphoid Irradiation in Renal Transplantation: Reduction and Elimination of Maintenance Immunosuppressive Drugs.- Adjuvant Methods of Immunomodulation for Transplantation.- Immunological Monitoring and Renal Transplantation.