Genetics of Colorectal Cancer

Epidemiology and Models of Colorectal Cancer.- Colorectal Cancer: Epidemiology.- Mouse Models of Intestinal Cancer.- Pathways to Colorectal Cancer.- The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer.- DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis.- Pathways and Pathology.- Germline Susceptibility – Mendelian and Other Syndromes.- Familial Adenomatous Polyposis.- DNA Mismatch Repair and Lynch Syndrome.- Additional Syndromes with Hereditary Predisposition to Colorectal Cancer.- Familial Colorectal Cancer Type X.- Families with Serrated Neoplasia of the Colon.- Peutz–Jeghers Syndrome.- Juvenile Polyposis.- BLM Mutation and Colorectal Cancer Susceptibility.- The Role of p53 in Colorectal Cancer.- Chromosomes 8q24 and 9p24: Associations with Colorectal Cancer.- Germline Susceptibility – Gene-Environment Interactions.- Genetic Variability in Folate-Mediated One-Carbon Metabolism and Risk of Colorectal Neoplasia.- Genetic Variability in NSAID Targets and NSAID-Metabolizing Enzymes and Colorectal Neoplasia.- The Role of Chemical Carcinogens and Their Biotransformation in Colorectal Cancer.- Calcium and Vitamin D.