Targeted Drug Strategies for Cancer and Inflammation
Springer-Verlag New York Inc.
978-1-4419-8416-6 (ISBN)
Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1).- Folate Receptors and Therapeutic Applications.- Hormonal Control of Folate Receptor Genes.- Folate Receptor Targeted Radionuclide Imaging Agents.- Folate receptor targeted thymidylate synthase inhibitors.- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.- Folate-receptor targeted cancer chemotherapy.- Anti-FR antibody generation and engineering: development of new therapeutic tools.- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases.- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-
Erscheint lt. Verlag | 6.5.2011 |
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Zusatzinfo | 8 Tables, black and white; XI, 254 p. With 1 4-page color insert. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 571 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
Medizin / Pharmazie ► Studium | |
ISBN-10 | 1-4419-8416-X / 144198416X |
ISBN-13 | 978-1-4419-8416-6 / 9781441984166 |
Zustand | Neuware |
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