The Principles of Clinical Cytogenetics

Steven L. Gersen, Martha B. Keagle (Herausgeber)

Buch | Softcover

567 Seiten

2010 | Softcover reprint of hardcover 1st ed. 1999
Humana Press Inc. (Verlag)
978-1-61737-070-0 (ISBN)

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This book provides a comprehensive, in-depth explanation of the basic concepts and interpretations involved in chromosome analysis, a critical technique in the diagnosis, prognosis, and monitoring of a wide variety of conditions. Designed for the health care provider who must use and explain the often complex results of these tests, this book details in understandable language the various applications of chromosome analysis in clinical settings and the clinical significance of abnormal results. In addition, the book offers an informative tutorial on basic laboratory procedures (including microscopy, photomicrography, automation, computerized karyotyping, and QA/QC), reports on novel synergistic technologies such as FISH, and discusses issues in genetic counseling. Enlightening and accessible, The Principles of Clinical Cytogenetics constitutes an indispensable reference for today's physicians and managed care practitioners who depend on the cytogenetics laboratory for the diagnosis of their patients' ailments.

Part I. Basic Concepts and Background. History of Clinical Cytogenetics, S. L. Gersen. DNA, Chromosomes, and Cell Division, M. Keagle and J. D. Brown. Human Chromosome Nomenclature: An Overview and Definition of Terms, A. Tharapel. Part II. Examining and Analyzing Chromosomes. Basic Laboratory Procedures, M. B. Keagle and S. L. Gersen. Microscopy and Photomicrography, C. McAleer. Quality Control and Quality Assurance, C. McAleer and S. L. Gersen. Automation in the Cytogenetics Laboratory, S. L. Gersen and J. Ginestet. Part III. Clinical Cytogenetics. Autosomal Aneuploidy, J.-C. C. Wang. Structural Chromosome Rearrangements, K. Kaiser-Rogers and K. Rao. Sex Chromosomes and Sex Chromosome Abnormalities, C. M. Powell. Prenatal Cytogenetics, L. M. Randolph. Cytogenetics of Spontaneous Abortion, S. M. V. Pflueger. Cancer Cytogenetics, A. W. Block. Part IV. Beyond Chromosomes. Fragile X: From Cytogenetics to Molecular Genetics, P. N. Howard-Peebles. Fluorescence In Situ Hybridization, J. K. Blancato. Genomic Imprinting and Uniparental Disomy, J.-C. C. Wang. Genetic Counseling, Y. Furman. Index.

Erscheint lt. Verlag	12.10.2010
Zusatzinfo	72 black & white illustrations, 13 colour illustrations, biography
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Gewicht	1075 g
Einbandart	Paperback
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	1-61737-070-3 / 1617370703
ISBN-13	978-1-61737-070-0 / 9781617370700
Zustand	Neuware