Mineralocorticoids and Hypertension

Physiological Basis of Mineralocorticoid Hormone Action.- Mineralocorticoid Receptors and Extrinsic Specificity-conferring Mechanisms.- Intracellular Action of Mineralocorticoids: The Role of the Flavin Coenzymes and Riboflavin Analogs in Hypertension.- Regulation of Mineralocorticoids.- Novel Control Mechanisms of Aldosterone Secretion.- The Diagnostic Value of Urinary Free 18-Hydroxycorticosterone in Primary Aldosteronism.- Acute and Chronic Regulation of Aldosterone Secretion in Man.- Radioimmunologic Methods in Aldosterone Diagnosis.- Pathophysiological Aspects of Mineralocorticoid Excess.- Mechanism for Escape from the Sodium-retaining Effects of Mineralocorticoids.- Mechanism of Mineralocorticoid-induced Hypertension.- The Role of "Mineralocorticoids", "Glucocorticoids" and "Hypertensinogenic" Steroids in ACTH-induced Hypertension.- Mechanism of Mineralocorticoid-induced Hypertension in Man.- Clinical Aspects of Mineralocorticoid-induced Hypertension.- Primary Aldosteronism and Other Mineralocorticoid Excess Syndromes in Hypertension: Incidence, Screening, and Diagnosis.- Differentiation of Mineralocorticoid-induced Hypertension.- Localization of the Adrenal Lesions in Primary Aldosteronism.- Is Idiopathic Hyperaldosteronism a Variant of Essential Hypertension or of Conn's Syndrome?.- Mineralocorticoids in Essential Hypertension.- Antimineralocorticoids.- Structure-Activity Relationship of Antimineralocorticoid Active Compounds.- The Relative Potency of Competitive and Non-competitive Mineralocorticoid Antagonists in Man.- Spironolactone in Essential Hypertension: Effects on Kidney Function and Plasma Electrolytes in Relation to Salt Intake.- Surgical Therapy of Primary Aldosteronism.