Red Cell Metabolism and Function

I. Relationship Between Red Cell Metabolism and Function.- Session 1 - A. Chanutin, Chairman.- Binding of Organic Phosphates to Hemoglobin A and Hemoglobin F.- Effect of Glutathione and Some Other Substances on the Oxygen Dissociation Curve of Hemoglobin and Experimental Therapy of Hemmorrhagic Shock with Solutions Enriched with Glutathione.- Variation in 2, 3-Diphosphoglycerate and ATP Levels in Human Erythrocytes and Effects on Oxygen Transport.- Binding of 2,3-Diphosphoglycerate (DPG) to Oxyhemoglobin; Levels and Effect of DPG on Oxygen Affinity of Normal and Abnormal Blood.- Session 2 - C.-H. deVerdier, Chairman.- Dependence of Oxyhemoglobin Dissociation and Intraerythrocytic 2,3-Diphosphoglycerate on Acid-Base Status of Blood I. In vitro Studies of Reduced and Oxygenated Blood.- II. Clinical and Experimental Studies.- Erythrocyte Glycolytic Intermediates and Cofactors Correlated with the Haemoglobin Concentration in Human Neonates and Adults.- Studies of Red Cell Glycolysis and Interactions with Carbon Monoxide, Smoking, and Altitude.- II. Metabolic Control Mechanisms in the Red Cell.- Session 3 - A. Chanutin, Chairman.- General Features of Metabolic Control as Applied to the Erythrocyte.- The Enzymes 2,3-Diphosphoglycerate Metabolism in the Human Red Cell.- Metabolism of 2,3-Diphosphoglycerate in Red Blood Cells Under Various Experimental Conditions.- III. Interaction of the Cardiac, Pulmonary, and Erythrocyte Systems in Respiratory Homeostasis.- Session 4 - R. Grover, Chairman.- The Respiratory Function of the Blood.- Systemic Oxygen Transport.- Adaptation to Hypoxia.- Adaptation of the Red Blood Cell to Muscular Exercise.- A Comparison of Mechanisms of Oxygen Transport Among Several Mammalian Species.- IV. Erythrocyte Function after Blood Storage.- Session 5 - G. Bartlett, Chairman.- Patterns of Phosphate Compounds in Red Blood Cells of Man and Animals.- Biological Alterations Occurring During Red Cell Preservation.- The Prediction of Poststorage Red Cell Viability from ATP Levels.- Application of a Mechanized Method for the Determination of Different Glycolytic Intermediates in the Routine Quality Control of Red Cells.- Red Cell 2,3-DPG, ATP, and Creatine Levels in Preserved Cells and in Patients with Red Cell Mass Deficits or with Cardiopulmonary Insufficiency.- The Hemoglobin Function of Blood Stored at 4 C.- Appendix - Discussion of Papers in Order of Presentation.