Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders

From the considerable expertise of the Mayo Clinic, this book spans the gamut from multiple myeloma, the most frequent and most serious of the monoclonal gammopathies, to the rarest related disorders. Laboratory evaluation, associations with nonhematologic disorders, monoclonal gammopathies of undetermined significance, the more obscure plasma cell dyscrasias, amyloidosis, other immunoglobulin deposition disorders, Waldenstr÷m macroglobulinemia, and Fanconi anemia are among the topics covered. Particular attention is paid to multiple myeloma: history, pathogenesis, clinical and laboratory diagnosis, modern therapy, and prognosis.

1 Monoclonal Gammopathies of Undetermined Significance and Smoldering Multiple Myeloma.- 2 Neuropathy Associated With Plasma Cell Proliferative Disorders.- 3 Multiple Myeloma.- 4 Solitary Plasmacytoma of Bone and Extramedullary Plasmacytoma.- 5 Plasma Cell Leukemia.- 6 Heavy Chain Diseases.- 7 Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis, AL).- 8 Light Chain Deposition Disease.- 9 Waldenström Macroglobulinemia.- 10 Cryoglobulinemia.- 11 Acquired Fanconi Syndrome Associated With Monoclonal Plasma Cell Disorders.