Diabetes - Perspectives in Drug Therapy

Mathias Schwanstecher (Herausgeber)

Buch | Hardcover
XIII, 408 Seiten
2011 | 2011
Springer Berlin (Verlag)
978-3-642-17213-7 (ISBN)
427,99 inkl. MwSt
The chapters of this book report cutting-edge research on molecular events in adiposity and type-2 diabetes, opening the way for innovative drug-based therapeutic strategies. The book will help all those who wish to keep abreast of developments in the field.

Every 5 seconds someone somewhere is diagnosed with diabetes, and every 10 seconds someone dies of it. Even worse, worldwide incidence rates still inexorably escalate. Thus, it is pressing to envisage the extent of the diabetes problem and ensure synergistic approaches aiming in alleviation of its ghastly toll.
The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.

Preface. Targeting type 2 diabetes. Dual acting and pan-PPAR activators as potential anti-diabetic therapies. GLP-agonists and Dipeptidyl-Peptidase IV Inhibitors. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. SGLT Inhibitors as New Therapeutic Tools in the Treatment of Diabetes. Inhibitors of 11b-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy. Nampt and its potential role in inflammation and type 2 diabetes . Inhibition of ganglioside biosynthesis as a novel therapeutic approach in insulin resistance. Overcoming Insulin Resistance with Ciliary Neurotrophic Factor. Thermogenesis and related metabolic targets in anti-diabetic therapy. Interleukin targeted therapy for metabolic syndrome and type 2 diabetes. Fructose-1, 6-Bisphosphatase Inhibitors for Reducing Excessive Endogenous Glucose Production in Type 2 Diabetes. AMP-activated protein kinase and metabolic control. Mitochondria as potential targets in antidiabetic therapy . Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects

Erscheint lt. Verlag 14.3.2011
Reihe/Serie Handbook of Experimental Pharmacology
Zusatzinfo XIII, 408 p. 69 illus.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 762 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Schlagworte antidiabetic therapy • Diabetes • insulin resistance • Obesity • ß-cell
ISBN-10 3-642-17213-X / 364217213X
ISBN-13 978-3-642-17213-7 / 9783642172137
Zustand Neuware
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