Human Growth Hormone

I.- The National Hormone and Pituitary Program: Achievements and Current Goals.- II.- The NIADDK Hormone Distribution Program.- I. Hypopituitarism and Hyperpituitarism: Clinical Studies.- 1 A Perspective on Growth Hormone and Growth: A Tribute to Maurice Raben.- 2 Growth Hormone Hypersecretory States.- 3 Clinical Features, Tests, and Causes of Growth Hormone Deficiency.- 4 Dose-Response Relationships in Growth Hormone Therapy.- 5 Dose Studies for Human Growth Hormone in Hypopituitarism: Current Recommendations.- 6 Subcutaneous versus Intramuscular Injection of Human Growth Hormone.- 7 Psychosocial Impact of Long-Term Growth Hormone Therapy.- II. Human Growth Hormone in other Forms of Short Stature: Gene Studies.- 8 Growth-Stimulating Effects of Human Growth Hormone Therapy in Turner's Syndrome: Preliminary Report.- 9 Turner's Syndrome and Human Growth Hormone: Biochemical Studies.- 10 Short Normal Children in Therapeutic Trial of Human Growth Hormone Responsiveness.- 11 Bioinactive Growth Hormone and Secondary Growth Hormone Deficiency.- 12 The Hyposomatomedinemic Short Child.- 13 Growth Hormone-Resistant Syndromes.- 14 Hormonal Regulation of Growth Hormone Gene Expression.- 15 Organization and Function of the Growth Hormone Gene Cluster.- 16 Defects of Growth Hormone Genes: Clinical Syndromes.- III. Biosynthesis of Human Growth Hormone: Clinical Studies.- 17 Standards for Growth Hormone.- 18 Recombinant DNA Synthesis of Human Growth Hormone.- 19 Methionyl Human Growth Hormone (Somatonorm(R)): Purity and Properties.- 20 Clinical Studies with Recombinant-DNA-Derived Methionyl-Human Growth Hormone in Growth Hormone-Deficient Children.- 21 Experience with Methionyl Growth Hormone (Somatonorm I) in the United Kingdom.- 22 Clinical Experience with Biosynthetic Growth Hormone (III).- IV. Control of Growth Hormone Secretion, Growth Hormone-Releasing Factor, Somatostatin.- 23 Regulation of Growth Hormone Secretion.- 24 Chemical, Anatomical and Physiological Studies on Human Pancreatic and Rat Hypothalamic Growth Hormone-Releasing Factor.- 25 Growth Hormone-Releasing Factor: Isolation, Characterization, and Physiology.- 26 Ectopic Growth Hormone-Releasing Factor Syndromes.- 27 Growth Hormone-Releasing Factor.- 28 Acromegaly Related to Tumoral Secretion of Growth Hormone-Releasing Factor.- 29 Studies with Growth Hormone-Releasing Factor (GRF) in the Human: Effect of a Single Pulse, Continuous Infusion, or Multiple Pulses of GRF on Growth Hormone (GH) Release in Normal and GH-Deficient Children and Adults.- 30 Somatostatin: Biosynthesis, Regulation of Secretion, and Role in Growth Hormone Regulation.- V. Chemistry of Human Growth Hormone: Physiological Studies.- 31 Conformational Comparison of Human Pituitary Growth Hormone and Human Chorionic Somatomammotropin (Human Placental Lactogen) by Second-Order Absorption Spectroscopy.- 32 Multiple Forms of Human Growth Hormone.- 33 The Multivalent Nature of Growth Hormone.- 34 Isolation of Growth Hormone Receptor.- 35 Structural Studies of the Growth Hormone Receptor by Affinity Labeling.- 36 Binding of Growth Hormone to Hepatic Receptors.- 37 Growth Hormone Action on Adipocytes.- VI. Somatomedin/Insulinlike Growth Factor.- 38 Chemistry of Somatomedins.- 39 Synthetic Somatomedin C/Insulinlike Growth Factor I.- 40 Biosynthesis of Rat Insulinlike Growth Factor II in Intact Cells and Cell-Free Translation.- 41 The Insulinlike Growth Factor Receptors.- 42 The Somatomedin Binding Proteins.- 43 Direct Action of Growth Hormone on Cartilage Growth.- 44 Increased Somatomedin Inhibitors in Renal Failure.- 45 Action of Somatomedins on Cell Growth: Effect of Selective Neutralization of Somatomedin C (Insulinlike Growth Factor I) with a Monoclonal Antibody.- 46 Regulation of Serum Insulinlike Growth Factor II.- 47 Somatomedin C/Insulinlike Growth Factor I: Regulation and Clinical Applications.- 48 Somatomedin/Insulinlike Growth Factor in the Human Fetus.- 49 Somatomedin C in the Ovine Fetus and Neonate.- Contributors.