Adenoviruses: Model and Vectors in Virus-Host Interactions -

Adenoviruses: Model and Vectors in Virus-Host Interactions

Immune System, Oncogenesis, Gene Therapy

Walter Doerfler, Petra Böhm (Herausgeber)

Buch | Softcover
IX, 368 Seiten
2010 | 1. Softcover reprint of hardcover 1st ed. 2004
Springer Berlin (Verlag)
978-3-642-05715-1 (ISBN)
213,99 inkl. MwSt

 After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy. 

List of Contents.- 1 Immune System.- Evasion of the Immune System by Adenoviruses.- Immune Evasion by Adenovirus E3 Proteins: Exploitation of Intracellular Trafficking Pathways.- The Coxsackie-Adenovirus Receptor-A New Receptor in the Immunoglobulin Family Involved in Cell Adhesion.- Mechanisms of E3 Modulation of Immune and Inflammatory Responses.- 2 Oncogenesis.- Modulation of Oncogenic Transformation by the Human Adenovirus E1A C-Terminal Region.- Cell Transformation by Human Adenoviruses.- Tumorigenesis by Adenovirus Type 12 in Newborn Syrian Hamsters.- E1A-Based Determinants of Oncogenicity in Human Adenovirus Groups A and C.- 3 Gene Therapy.- Replicating Adenoviruses in Cancer Therapy.- Adenovirus Vectors: Biology, Design, and Production.

Erscheint lt. Verlag 9.12.2010
Reihe/Serie Current Topics in Microbiology and Immunology
Zusatzinfo IX, 368 p. 50 illus., 5 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 642 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Cell • Coxsackie Receptor • Gene • gene therapy • gene transfer • Gene Transfer Vehicle • immune system • Immunoglobulin • Oncogenesis • Oncogenic Transformation • Protein • proteins • Tumorigenesis • Virus
ISBN-10 3-642-05715-2 / 3642057152
ISBN-13 978-3-642-05715-1 / 9783642057151
Zustand Neuware
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