Fundamentals of Cell Immobilisation Biotechnology

1 Materials for Cell Immobilisation/Encapsulation.- Biomaterials for cell immobilization: A look at carrier design.- Alginate as a carrier for cell immobilisation.- Entrapment in LentiKats®: Encapsulation of various biocatalysts — bacteria, fungi, yeast or enzymes into polyvinyl alcohol based hydrogel particles.- Starches as encapsulation materials.- Proteins: versatile materials for encapsulation.- Polyelectrolyte complexes for microcapsule formation.- Pre-formed carriers for cell immobilisation.- Microcarriers for animal cell culture.- 2 Methods and Technologies for Cell Immobilisation/Encapsulation.- Microcapsule formulation and formation.- Liquid core caspules for applications in biotechnology.- Direct compression — novel method for encapsulation of probiotic cells.- Cell immobilisation in pre-formed porous matrices.- Whole cell immobilization in chopped hollow fibres.- Use of vibration technology for jet break-up for encapsulation of cells and liquids in monodisperse microcapsules.- Immobilization of cells and enzymes using electrostatic droplet generation.- The JetCutter technology.- Industrial scale encapsulation of cells using emulsification/dispersion technologies.- Atomisation techniques for immobilisation of cells in micro gel beads.- Spray coating and drying processes.- 3 Carrier Characterisation and Bioreactor Design.- Diffusive mass transfer in immobilised cell systems.- Characterization of microcapsules.- Immobilised cell bioreactors.- 4 Physiology of Immobilised Cells: Experimental Characterisation and Mathematical Modelling.- Applications of NMR spectroscopy and imaging to the study of immobilised cell physiology.- Physiology of immobilised microbial cells.- Modelling immobilised-cell processes: Application to integrated nitrogen removal withco-immobilised microorganisms.- Biofilm modelling.