NF-kB in Health and Disease
Seiten
2011
|
2011
Springer Berlin (Verlag)
978-3-642-16016-5 (ISBN)
Springer Berlin (Verlag)
978-3-642-16016-5 (ISBN)
Nearly 25 years of research have uncovered many diverse functions for the dimeric transcription factor NF-kappaB. NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation.
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Preface.- Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms.- IKK regulation and human genetics.- Specialized chromatin patterns in the control of inflammatory gene expression.- Macrophages and NF-kappaB in Cancer.- NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster.- IKK and NF-kappaB mediated functions in carcinogenesis.- Control of NF-kappaB activity by proteolysis.- NF-kappaB as a target for oncogenic viruses.- NF-kappaB and Innate Immunity.- Inhibition of NF-kappaB signaling as a strategy in disease therapy.- NF- B and mucosal homeostasis.- NF-kappaB In liver cancer - the plot thickens.- Subject index.
Erscheint lt. Verlag | 6.5.2011 |
---|---|
Reihe/Serie | Current Topics in Microbiology and Immunology |
Zusatzinfo | VIII, 268 p. |
Verlagsort | Berlin |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 553 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Studium | |
Schlagworte | cell survival • inflammatory gene expression • mucosal homeostasis • NEMO molecule • oncogenic viruses • regulation of NF-kB signalling • tumor-associated macrophages |
ISBN-10 | 3-642-16016-6 / 3642160166 |
ISBN-13 | 978-3-642-16016-5 / 9783642160165 |
Zustand | Neuware |
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