Radiation Biology of Medical Imaging

The authors of this new edition have a combined teaching experience of over 100 years: Charles Kelsey is the author of Essentials of Radiology Physics (W. H. Green, 1985) and Essentials of Radiologic Science (McGraw-Hill, 2002). Both of these radiography-targeted books include chapters on radiation biology. He has taught radiation biology for over 40 years to x-ray technologists, medical physicists, radiology/radiation oncology residents and nuclear engineering students. Philip H. Heintz, PhD, is Chairman of the AAPM subcommittee on radiology residents Physics (including radiation biology), and director of the medical physics education program at the University of New Mexico. He has taught radiation biology for over 30 years to medical physicists, radiology/radiation oncology residents, nuclear engineering students, and x-ray technologists. Educational initiatives include extensive work with the ASRT on a physics and biological curriculum for x-ray technologists, as well as very active contribution to the web-based education committee for diagnostic radiology residents of the AAPM/RSNA.

Acknowledgments vii

Introduction ix

1 Anatomy and Physiology 1

2 The Cell 19

3 Radiation Characteristics and Units 41

4 Radiation Interactions with Tissue 61

5 Cell Survival Curves 81

6 Dna and Genetics 105

7 Radiation Damage and Repair of Cells 125

8 Normal and Malignant Cells 145

9 Radiation Effects on Tissues and Organs 161

10 Whole Body Radiation Effects 179

11 Radiation Treatment of Cancer 191

12 Radiation Biology of Diagnostic Imaging 203

13 Nuclear Medicine Radiation Biology 219

14 Environmental Radiation 241

15 Regulations and Risk 255

16 Biological Effects of Ultrasound 269

17 Biological Effects of Magnetic Resonance Imaging 281

Answers to Odd-numbered Questions 297

Index 301