Fibrin Sealant in Operative Medicine

I. Principles of Fibrin Sealing.- The Importance of Fibrin in Wound Repair.- Fibrin Sealant and Its Modes of Application.- Properties of Different Tissue Sealants with Special Emphasis on Fibrinogen-Based Preparations.- Lysis and Absorption of Fibrin Sealant (Tissucol/Tisseel) (In Vitro and in Vivo Experiments).- Preliminary Results of a Randomized Controlled Study on the Risk of Hepatitis Transmission of a Two-Component Fibrin Sealant (Tissucol/Tisseel).- II. Otorhinolaryngology.- Remarks on a Daily Use of Tissucol (Tisseel) during 5 Years in Otology and Otoneurosurgery.- Selected Aspects of ENT Surgery in Central Midfacial Lesions.- Use of Fibrin Glue in Otorhinolaryngology.- Endoscopic Lateral Cordopexy.- The Use of Fibrin Sealant in Ear, Nose and Throat Surgery.- The Use of Fibrin Glue in Tympanoplasty.- Tissucol (Tisseel) in Tympanoplasty: Personal Observations.- The Use of Fibrin Sealant in Middle Ear Surgery and in Otoneurosurgery.- Simplified Application of Fibrinous Glue in Middle-Ear Surgery.- A New Application Method for Fibrin Sealant: The Glue Gun.- Fibrin Sealant (Tissucol/Tisseel) in Ear Surgery (A 4-Year Experience).- En Bloc Ethmoidectomy Through the Combined Craniofacial Approach: Surgical Technique.- Local Application of Human Fibrin Seal (Tissucol/Tisseel) in Tonsillectomies and Adenectomies in Patients with Bleeding Disorders. Ten Years' Clinical Experience.- The Use of Fibrin Glue in Auricular Surgery.- Reconstruction of the Open Mastoidectomized Ear: Two Surgical Techniques.- Fibrinogen Glue in Reconstructive Surgery of the Skull Base.