Experimental Hematology Today-1985

I. Hematopoietic Regulators.- 1. Role of T-Lymphocyte Colony Enhancing Factor, TLCEF, in the Induction of CFU-TL.- 2. Thymic Hormones in Thymus Recovery from Radiation Injury.- 3. Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy between Phorbol Esters and Calcium Ionophores.- 4. Dependence of CFU-S Proliferation on the CFU-S Population.- 5. Interaction of Interleukin 3 with Pluripotent Hematopoietic Stem Cells.- 6. In Vivo Effects of Urinary Extracts of Patients with Aplastic Anemia on Rat Platelet Production and Megakaryocyte Progenitors in Murine Spleen and Bone Marrow.- 7. Inhibitor(s) of Biologically Active Erythropoietin in Concentrated Human Sera.- II. Hematopoietic Microenvironment.- 8. Establishment of Bone Marrow Stromal Cell Cultures and Permanent Clonal Stromal Cell Lines from Osteopetrotic (mi/mi) and Steel Mutant (Sl/Sld Mice: Studies of Bone Resorption by Engrafted Hemopoietic Stem Cells In Vitro.- 9. Monoclonal Antibodies Identify Specific Determinants on Reticular Cells in Murine Embryonic and Adult Hemopoietic Stroma.- 10. Stromal Cell Lines from Mouse Bone Marrow: A Model System for the Study of the Hemopoietic Microenvironment.- III. Differentiation of Normal & Leukemic Cells.- 11. Glycosphingolipids as Specific Differentiation-Markers and Differentiation-Inducers for Human Myelogenous Leukemia Cells: A Monosialyl Glycosphingolipid, Ganglioside GM3, is Highly Potent for Induction of Monocytic Differentiation of Human Myeloid and Monocytoid Cell Lines, HL-60 and U937 Cells.- 12. Properties of a T-Lymphocyte Derived Differentiation Inducing Factor (DIF) for the Myeloid Leukemic Cell Line HL-60.- 13. Interactions of Differentiation Inducing Agents In Vitro Provide Insight into Molecular Mechanisms of Differentiation and Identify Synergistic Combinations Effective In Vivo.- IV. Leukemic Cells in Leukemogenesis.- 14. Immunoglobulin and T-Cell Receptor Gene Rearrangements in Human Acute Leukemias.- 15. Immunological and Molecular Classification of Human Leukemias.- 16. Oncogenes in Chronic Myelogenous Leukemia.- 17. Response to an Active Vitamin D3 Metabolite of Transplantable Human Myeloid Leukemic Cell Lines in Adult Nude Mice.- V. Bone Marrow Transplantation.- 18. Risk Factors for Acute Graft-vs-Host Disease in Humans.- 19. Autologous Marrow Transplantation for Malignant Lymphoma.- 20. The Influence of T-Cell Depletion by Monoclonal Antibodies on Repopulating Hemopoietic Stem Cells and Their Efficacy in Preventing GvHD in Rhesus Monkeys.- 21. Review of the Effects of Anti-T-Cell Monoclonal Antibodies on Major and Minor GvHR in the Mouse.