Mitochondrial Genetics and Cancer
Springer Berlin (Verlag)
978-3-642-11415-1 (ISBN)
Gabriel D. Dakubo is the founder of Mito-Onc Consultancy, a pioneer consulting firm that provides evidence-based advice on discovery, validation and regulatory submission of cancer biomarkers based on mitochondrial genomic alterations.
PART 1: GENERAL OVERVIEW OF MITOCHONDRIAL GENETICS AND FUNCTIONS1. Basic Mitochondrial Genetics, Bioenergetics and Biogenesis2. The Warburg Phenomenon and Other Metabolic Alterations of Cancer Cells3. Mitochondrial Control of Apoptosis and Cancer4. Mitochondrial-to-Nuclear Communications in CancerPART 2: MITOCHONDRIAL GENETIC ALTERATIONS IN CANCER5. Types of Mitochondrial Genetic Alterations in Cancer6. Mitochondrial Genetic Alterations in Cancer I: Skin, Head and Neck,7. Mitochondrial Genetic Alterations in Cancer II: Renal, Urinary Bladder, Prostate, Ovarian, Endometrial, Cervical, Nervous System, Hematologic, and Connective Tissue Cancers8. Mitochondrial Genome Rearrangements and Copy Number Changes in Cancer9. Functional Importance of Mitochondrial Genetic Alterations in Cancer10. The Role of Mitochondrial Reactive Oxygen Species in CancerPART 3: CLINICAL APPLICATIONS OF MITOCHONDRIAL GENOME CHANGES IN CANCER11. Mitochondrial DNA Measurement in Exfoliated Cells for Cancer Detection and Monitoring - the Copy Number Advantage12. Early Cancer Detection and Monitoring Using Changes in the Mitochondrial Genome as Biosensors13. Analysis of Mitochondrial Genome Alterations in Cancer14. "Mitocans": Agents Targeting Mitochondrial to Kill Cancer Cells
Erscheint lt. Verlag | 13.4.2010 |
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Zusatzinfo | XV, 356 p. |
Verlagsort | Berlin |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 711 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Schlagworte | Apoptosis • Cancer Therapy • Carcinogenesis • DNA • Genetics • Hardcover, Softcover / Medizin/Nichtklinische Fächer • mitochondrial genome mutations • tissue |
ISBN-10 | 3-642-11415-6 / 3642114156 |
ISBN-13 | 978-3-642-11415-1 / 9783642114151 |
Zustand | Neuware |
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