Diabetes Mellitus: Pathophysiology and Therapy

Pathophysiology.- Etiology.- Epidemiology - Its Contribution to Understanding of the Etiology, Pathogenesis, and Prevention of Diabetes Mellitus.- Genetics of Diabetes Mellitus.- On the Pathogenesis of Insulin-Dependent Diabetes Mellitus - A Discussion of Three Recently Proposed Models.- Challenging Views on the Pathogenesis of Type I (Insulin-Dependent) Diabetes Mellitus.- Islet Amyloid and Type 2 Diabetes.- Physiology and Pathophysiology.- Insulin Receptor: Role of Receptor Tyrosine Kinase in Insulin Signalling and Action.- The Kinetics of Insulin, C-Peptide, and Proinsulin in Normal and Diabetic Man.- Cell Biology of Insulin Action on Glucose Transport and Its Perturbation in Diabetes Mellitus.- Mechanisms of Insulin Resistance in Obese and Type II Diabetic Subjects.- Abnormal Glucagon Secretion in Type 2 (Noninsulin-Dependent) Diabetes Mellitus: Causes and Consequences.- Animal Models.- Physiopathology and Possible Etiology of Hormonal Dysregulations and Insulin Resistance in Obese Rats: a Potential Model for Some Human Obesity.- Models for Studying Diabetic Complications.- Pharmacology.- Insulin Analogues - Potentials for Improving Diabetes Treatment.- Metabolic Inhibitors in the Treatment of Diabetes Mellitus.- Inhibitors Influencing Carbohydrate Absorption.- Therapy.- Comprehensive Approach to the Treatment of Diabetes Mellitus.- Why and How to Involve the Diabetic Patient in his Treatment.- Prevention of Late Complications.- Advanced Non-Enzymatic Tissue Glycosylation: Biochemical Basis of Late Diabetic Complications.- Is it Possible to Prevent Late Complications of Diabetes Mellitus?.- Recent Aspects of Insulin Therapy.- Long-Term Efficacy and Safety of Intensified Insulin Treatment Strategies.- Is Human Insulin Better than Animal Insulin in the Treatmentof Insulin-Dependent Diabetes Mellitus?.- Specific Problems of Diabetes Mellitus in Youth.- Natural History of Diabetes Mellitus in Children.- Particular Aspects of the Management of Diabetes in Children.- The Pregnant Diabetic.- The State of the Art in Diabetic Pregnancy.- Relationship Between Maternal Glucose Levels and Congenital Malformations in the Infant of the Diabetic Mother.- Pancreas and Islet Transplantation.- State of the Art in Pancreas Transplantation.- What Future for Islet Transplantation in Man?.- Diet.- Aims of Diet in Diabetes Management.- Practicability of Diet in Diabetes Management.- New Aspects of Diabetes Treatment.- Induction of Partial Remission and Enhancement of Beta-Cell Function By Cyclosporin in Type I Diabetes.- Role of Abnormal Free Fatty Acid Metabolism in the Pathogenesis and Treatment of Noninsulin-Dependent Diabetes Mellitus.