Handbook of Evidence-Based Critical Care

This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references.

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Learningwithoutthinkingisuseless. Thinkingwithoutlearningis dangerous -Confucius Sincethepublicationofthe?rsteditionofTheHandbookofEvidence- BasedCriticalCarein2001,thelandscapeofcriticalcaremedicinehas changed enormously. Numerous randomized controlled studies (RCTs) thathavechangedthedailypracticeofcriticalcaremedicinehavebeen published. Furthermore, our understanding of the complex pathophy- ologyofthecriticallyillandinjuredhasadvanced,newtherapieshave emerged (and some have fallen by the wayside), and we have re?ned howwemonitorandmanageourpatients. Wehavealsorecognizedour limitationsandimprovedend-of-lifecare. Inall,wearewiserandmore attuned to the challenges of providing care to the sickest of the sick. However,thebasicguidingprinciplesofcriticalcaremedicinehavenot changed;compassionate,dedicatedandthoughtfulclinicians,whoeva- atethefunctioningofthe"whole"patient,pondertheirdiseaseprocesses and pathophysiology and provide the highest level of evidence-based interventions with the goal of restoring the patient to a quality of life whichhe/shevalues.
ThesecondeditionofTheHandbookofEvidence- BasedCriticalCarechroniclestheremarkableprogressmadeinthelast decadeandsetsthestageforwhatisyettocome! Thefocusofthishandbookisonissuesthatpertainspeci?callytothe ICU. Assuchthereaderisreferredtostandardmedicalandsurgicaltexts aswellasonlineresourcesformorecompleteinformationonthewide spectrumofconditionsanddiseasesfromwhichICUpatientsmaysuffer. PaulEllisMarik Norfolk,Virginia ix Contents Part I. Introduction to Critical Care Medicine 1. Evidence-BasedCriticalCare 3 2. ClassicCriticalCarePapers 7 3. CriticalCareMedicine101 13 4. HouseOf?cers'Guideline1:Housekeeping 17 5. Admission-DischargeCriteria 23 6. HouseOf?cers'Guidelines2:Procedures 31 7. ChronicCriticalIllness 43 8. FluidResuscitationandVolumeAssessment 55 9. SedationandAnalgesia 79 10. Sepsis 95 11. Catheter-RelatedBloodstreamInfection 117 12. Antibiotics 123 13. Fever 133 Part II. Respiratory 14. MechanicalVentilation101 153 15. Non-invasivePositive-PressureVentilation 175 16. Weaning(Liberation) 183 17. Ventilator-AssociatedPneumonia 193 18. Community-AcquiredPneumonia 205 19. ARDS 215 xi xii Contents 20. AspirationPneumoniaandPneumonitis 233 21.
DeepVenousThrombosis-PulmonaryEmbolism 245 22. COPDExacerbation 253 23. AcuteSevereAsthma 261 24. PleuralEffusionsandAtelectasis 271 Part III. Cardiac 25. HypertensiveCrises 281 26. AcuteCoronarySyndromes 295 27. STSegmentElevationMyocardialInfarction 301 28. Arrhythmias 311 29. AcuteDecompensatedCardiacFailure 323 30. TakotsuboCardiomyopathy 343 Part IV. Gastrointestinal 31. Nutrition 351 32. StressUlcerProphylaxis 361 33. ChronicLiverFailure 371 34. AlcoholicHepatitis 381 35. FulminantHepaticFailure 385 36. GIBleeding 393 37. Pancreatitis 403 38. DiarrheaandConstipation 411 Part V. Metabolic 39. StressHyperglycemiaandGlycemicControl 421 40. AdrenalInsuf?ciencyandCIRCI 427 41. Hypo-andHypercalcemia 435 42. ElectrolyteDisturbances 443 43. Acid-BaseDisturbances 453 44.