Copper Transport and Its Disorders

1. Copper Transport in Mammals.- 2. Models to Evaluate Health Risks Derived from Copper Exposure/Intake in Humans.- 3. Cu Metabolism in the Liver.- 4. Multiple Forms of the Menkes Cu-ATPase.- 5. The Cell Biology of the Menkes Disease Protein.- 6. Functional Analysis of the Menkes Protein (MNK) Expressed from a cDNA Construct.- 7. Mutation Spectrum of ATP7A, the Gene Defective in Menkes Disease.- 8. Animal Models of Menkes Disease.- 9. Developmental Expression of the Mouse Mottled and Toxic Milk Genes.- 10. The Treatment of Wilson’s Disease.- 11. Indian Childhood Cirrhosis and Tyrolean Childhood Cirrhosis: Disorders of a Copper Transport Gene?.- 12. Animal Models of Wilson’s Disease.- 13. Copper-Binding Properties of the N-Terminus of the Menkes Protein.- 14. Expression, Purification, and Metal Binding Characteristics of the Putative Copper Binding Domain from the Wilson Disease Copper Transporting ATPase (ATP7B).- 15. Structure/Function Relationships in Ceruloplasmin.- 16. Autoxidation of Amyloid Precursor Protein and Formation of Reactive Oxygen Species.- 17. Copper-Zinc Superoxide Dismutase and ALS.- 18. A Study of the Dual Role of Copper in Superoxide Dismutase as Antioxidant and Pro-Oxidant in Cellular Models of Amyotrophic Lateral Sclerosis.- 19. The Effect of Copper on Tight Junctional Permeability in a Human Intestinal Cell Line (Caco-2).- 20. Metal Regulation of Metallothionein Gene Transcription in Mammals.- 21. Copper-Regulatory Domain Involved in Gene Expression.- 22. Intracellular Pathways of Copper Trafficking in Yeast and Humans.- 23. Copper Homeostasis in Enterococcus hirae.