Human Spermatozoa
Nova Science Publishers Inc (Verlag)
978-1-60876-401-3 (ISBN)
Spermatozoa is the basic human male germ cell. This gametocyte plays an important role in fertilisation. In the past five years, new improvements in diagnosis have allowed us to assess male fertility potential with a new perspective studying with demonstrated role in sperm physiology. Furthermore, it is demonstrated that infertile men have high levels of sperm DNA damages and a small percentage of spermatozoa from fertile men also possess detectable levels of DNA damage. This book examines several of the factors that may be involved in sperm chromatin and DNA anomalies, including intra and extra testicular factors. Furthermore, sperm capacitation is a complex physiological process that involves biochemical, biophysical, molecular and metabolic modifications of all sperm domains. Some important events related to the capacitation process of sperm is examined as well. The biological role of the proteasome during sperm capacitation and the acrosome reaction and its relationship with protein phosphorylation and dephosphorylation during these processes is explored as well. Other chapters in this book highlight the pivotal role of transmission electron microscopy (TEM) analysis in the diagnosis of human sperm pathologies, the barrier methods currently available to men for regulating their fertility, a discussion of the current understanding of gene transfer to the testis, a new perspectives for the study of mycoplasmal and chlamydial infections of human spermatozoa and a discussion of the present current knowledge on the mechanisms, molecules and cell signalling involved in sperm activating ability.
Preface; Sperm Nuclear Maturation: A Basic & Clinical Approach; Sperm Capacitation: Physiology, Molecular Mechanisms & Relevance for Fertilization; Role of the Human Sperm Proteasome during Capacitation & the Acrosome Reaction: Interaction with Protein Kinases & Phosphatases; Development & Maturation of Human Germ Cells & Disorders of Those Processes in Childhood; The Role of Transmission Electron Microscopy Analysis in Different Cases of Reduced Motility in Human Spermatozoa; Family Planning, Male Contraception, & Reproductive Health; Gene Therapy for Male Infertility: Potential & Limitation; Capacitation & Acrosome Reaction; Impaired Function of the Spermatozoa: Links with Mycoplasmal & Chlamydial Infections; Clinic Management of Men with Macrocephalic Sperm Head Syndrome; Mitochondria & Spermatozoa; Recent Insights into Spermatozoa Development & Ultrastructure in the Eucestoda; The Use of Pentoxifylline for Triggering the Movement of Testicular Sperm before their Use in Intracytoplasmic Sperm Injection in Men with Azoospermia; Sperm Induced Oocyte Activation; DNA Integrity & mRNA Expression Profile as Indicators of Sperm Quality & Assisted Reproduction Outcome; Effects of the seminal plasma proteins semenogelin (SEMG) / seminal vesicle secretion 2 (SVS2) on sperm fertility; Concern about the Possibility of Seminal Quality Decline in World Men Population; Sperm in Seropositive Males for HIV or HCV; The Heterochromatic Component of the Human Y Chromosome: A Genetic Wasteland or Something More? Suggestions from the Fruitfly; New Light on the Mechanism of Visible Light Therapy; Maintenance of the Cryopreserved Sperm in the Fertility Clinic is a Risky Task: Precautionary Note for the Clinics; Integrins in Human Spermatozoa: Their Role in Fertilization Process; Heavy Metal Contaminants & Male Reproductive Health; Interactions between Visible Light & Sperm Cells; Energy Consumption in Semen due to the Protein Glycosylation in Poorly Controlled Diabetes Mellitus; Spermatozoa in Zero Gravity Space: A New Concern; Oestrogen Usage in Gay: Effect on Spermatozoa?; Index.
| Erscheint lt. Verlag | 1.1.2011 |
|---|---|
| Zusatzinfo | Illustrations |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 260 x 180 mm |
| Gewicht | 1116 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie |
| ISBN-10 | 1-60876-401-X / 160876401X |
| ISBN-13 | 978-1-60876-401-3 / 9781608764013 |
| Zustand | Neuware |
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