Paediatric Haematology and Oncology

Simon Bailey is a paediatric oncologist based in Newcastle upon Tyne with a special interest in brain tumours and leukaemia. He did his initial medical training in Cape Town before specialising in paediatrics and paediatric oncology in Newcastle, which included a year in Wellington, New Zealand. He has a PhD in the molecular basis of steroid therapy in leukaemia. Rod Skinner qualified in medicine from Birmingham University in 1983. He trained in paediatrics and paediatric oncology in Newcastle upon Tyne, and was appointed Consultant and Honorary Clinical Senior Lecturer in Paediatric Oncology / Bone Marrow Transplantation in 1995. He was awarded a PhD in 1995 for clinical research into nephrotoxicity in children treated for cancer. His main clinical interests are treatment of childhood haematological malignancy and aplastic anaemia, and allogeneic bone marrow transplantation, with clinical research interests in late adverse effects of treatment for maligancy, and supportive care in children undergoing such treatment. He is currently Chairman of Children's Cancer and Leukaemia Group Supportive Care Group, and the Royal College of Paediatrics and Child Health Working Party on Immunisation in Immunocompromised Children.

INTRODUCTION TO PAEDIATRIC HAEMATOLOGY AND ONCOLOGY ; 1. Epidemiology of childhood cancer ; 2. Biology and genetics of childhood cancer ; 3. Paediatric oncology in the developing world ; GENERAL APPROACHES TO SUSPECTED CANCER ; 4. Abdominal mass ; 5. Initial diagnosis of brain tumours ; 6. The bleeding or bruising child ; 7. Lympadenopathy ; 8. Imaging of brain tumours ; 9. Imaging of non-CNS tumours ; HAEMATOLOGICAL AND ONCOLOGICAL EMERGENCIES ; GENERAL PRINCIPLES ; 11. Multimodality treatment ; 12. Chemotherapy ; 13. Paediatric radiotherapy ; 14. Surgery ; 15. Haemopoeitic stem cell transplantation ; 16. Clinical trials ; SUPPORTIVE CARE ; 17. Infection ; 18. Blood transfusion ; 19. Pain ; 20. Other aspects of supportive care ; LONG-TERM FOLLOW-UP ; 21. Long-term follow-up ; BENIGN HAEMATOLOGICAL DISEASES ; 22. Haemoglobinopathies ; 23. Haemostasis and thrombosis ; 24. Bone marrow failure ; 25. Other non-malignant causes of peripheral blood cytopenias ; MALIGNANT HAEMATOLOGICAL DISEASES ; 26. Acute lymphoblastic leukaemia (ALL) ; 27. Acute myeloid leukaemia ; 28. Acute leukaemia of ambiguous lineage (ALAL) ; 29. Myelodysplasia ; 30. Myeloproliferative diseases ; 31. Lymphoma ; SOLID TUMOURS ; 32. Neuroblastoma ; 33. Retinoblastoma ; 34. Renal tumours ; 35. Bone tumours ; 36. Extracranial germ cell tumours ; 37. Soft tissue sarcomas ; 38. Liver tumours ; CENTRAL NERVOUS SYSTEM TUMOURS ; 39. Central nervous system tumours ; OTHER CONDITIONS ; 40. Histiocytosis ; 41. Rare tumours ; NEW TREATMENT STRATEGIES ; 42. New treatment strategies ; Appendices ; Useful websites for children, young adults, and parents