Hematopoietic and Lymphoid Tissue in Culture

The Study of Hematopoietic and Lymphoid Tissues in Tissue Culture.- The Development of Tissue Culture Methods.- I. Hematopoietic Tissue In Vitro.- 1. Hematopoietic Tissue in Plasma Clot Culture.- 2. Monolayer Cultures of Hematopoietic Tissue.- 3. Suspension Cultures of Hematopoietic Tissue.- 4. Formation of Hematopoietic Foci in Agar Cultures.- 5. Organ Cultures of Hematopoietic Tissue.- Embryonic Liver.- Bone Marrow.- 6. A Comparative Assessment of the Various Methods of Hematopoietic Tissue Culture.- Duration of Hematopoiesis.- Myelopoiesis.- Erythropoiesis.- 7. Factors That Influence Differentiation of Hematopoietic Tissue In Vitro.- II. Possibilities of Differentiation of Cells Grown in Hematopoietic Tissue Cultures on Retransplantation In Vivo.- III. Lymphoid Tissue In Vitro.- 1. Lymphoid Tissue Explanted in a Plasma Clot.- Spleen.- Lymph Nodes.- Thymus.- Cells of the Peripheral Blood and Lymph.- 2. Monolayer Cultures of Lymphoid Tissue and Peripheral Blood Cells.- 3. Suspension Cultures of Lymphoid Tissue and Peripheral Blood Cells.- 4. Organ Cultures of Lymphoid Tissue.- Thymus.- Lymph Nodes.- 5. Comparison of Various Methods of Lymphoid Tissue Culture.- The Behavior of Lymphocytes.- Cell Transformations.- The Process of Regeneration.- Formation of Structures Characteristic of Interaction Between Lymphocytes and Stromal Cells.- IV. Immunological Functions of Lymphoid Tissue In Vitro.- 1. The Process of Antibody Formation.- Basic Mechanisms of Antibody Formation In Vivo and Aims of Research into This Process In Vitro.- Secondary Antibody Synthesis In Vitro.- Primary Antibody Synthesis In Vitro.- 2. The Delayed Hypersensitivity Reaction In Vitro.- Basic Mechanisms of the Delayed Hypersensitivity Reaction In Vivo and Aims of Research into This Process In Vitro.- Blast-Transformation, Recognition of Antigens, and the Cellular Immune Response In Vitro.- In Vitro Destruction of Target Cells by Lymphocytes from Preimmunized Donors.- Inhibition of Macrophage Migration.- The Simonsen Phenomenon.- Immunological Tolerance.- Conclusion.- V. Cell Lines in Lymphoid and Hematopoietic Tissue.- Conclusion.- Appendix. Recent Experience in Monolayer and Organ Cultures of Hematopoietic Tissue - E. A. Luriya and A. Ya. Fridenshtein.- 1. The Technique of Cloning Fibroblasts in Monolayer Cultures of Hematopoietic and Lymphoid Cells and Its Use to Study Stromal Precursor Cells.- 2. The Method of Multiple Organ Cultures of Hematopoietic and Lymphoid Tissue.- References.