The Local Cardiac Renin-Angiotensin Aldosterone System

Are Local Renin–Angiotensin Systems the Focal Points for Understanding Salt Sensitivity in Hypertension?.- Newer Insights into the Biochemical Physiology of the Renin–Angiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12).- Renin, Prorenin, and the (Pro)renin Receptor.- Intracellular Accumulation and Nuclear Trafficking of Angiotensin II and the Angiotensin II Type 1 Receptor.- Pathophysiologic Implications of Cell Swelling in the Failing Heart: Influence of Intracrine and Extracellular Renin–Angiotensin Systems.- Exploiting Rat Genetics to Investigate Hypertensive End-Organ Damage.- Alternative Renin Transcripts and Functions of Cytoplasmatic Renin.- Novel Aspects of the Cardiac Renin–Angiotensin System.- Intracrine Function from Angiotensin to Stem Cells.- Renin Cell Identity and Homeostasis.- Role of Renal Aminopeptidases and Angiotensin Type-2 (AT2) Receptors in Sodium Excretion and Hypertension.- Intrarenal Angiotensin II Augmentation in Hypertension.- Collecting Duct Renin: A Critical Linkin Angiotensin II-Dependent Hypertension.- Renin–Angiotensin–Aldosterone System and Cardiomyocyte Apoptosis in Hypertensive Heart Disease.- Upregulation of Angiotensin II Type 2 Receptor (agtr2) Attenuates Atherosclerotic Lesion Formation and Enhances Apoptosis in the LDL Receptor Knockout Mice Fed High Cholesterol Diet.- Salt and Heart: RAAS Involvement.- Cardiac Effects of Aldosterone, the Bad, but Is There Also a Good?.

From the reviews of the second edition:

“This book disseminates new findings about the local renin-angiotensin aldosterone system (RAAS) in the cardiovascular system and the kidneys … . This is a great resource for anyone doing research into any cell or tissue that is regulated or potentially regulated by RAAS. … Students beginning careers in research in this field will find this to be a great account of current research … . As a gastrointestinal physiologist with a long-time interest in hormonal regulation of cell function, I found this book intriguing.” (David L. Osborne, Doody’s Review Service, June, 2010)