Staphylococci in Human Disease

Kent B. Crossley MD University of Minnesota Medical School, MN, USA Kimberly K. Jefferson PhD Virginia Commonwealth University School of Medicine, VA, USA Gordon L. Archer MD Virginia Commonwealth University School of Medicine, VA, USA Vance G. Fowler Jr. MD, MHS Duke University Medical Center, NC, USA

Section I: The Organisms Biology and Taxonomy. 1 The biology of staphylococci ( Greg A. Somerville and Richard A. Proctor ). 2 Genomics of the Staphylococci. ( Steven R. Gill ). 3 The evolution and taxonomy of staphylococci ( Barry N. Kreiswirth, Barun Mathema, Jose R. Mediavilla and Liang Chen ). 4 The molecular basis of pathogenicity ( Mark S. Smeltzer, Chia Y. Lee, Nada Harik and Mark E. Hart ). 5 Adaptation to stress: biofilms and small colony variants ( Karl M. Thompson and Kimberly K Jefferson ). 6 Exotoxins ( Patrick M. Schlievert, John K. McCormick, Gregory A. Bohach and Douglas H. Ohlendorf ). 7 Host Defense Against Staphylococcal Infection. 7a The mechanism of host defense ( Hattie D. Gresham ). 7b Evasion of Host Defenses ( Timothy J. Foster ). Antimicrobial Resistance in Staphylococci. 8 Resistance to beta-lactam antibiotics ( Brigitte Berger-Bachi, Maria Magdalena Senn, Miram Ender, Kati Seidl, Judith Hubscher, Bettina Schulthess, Roni Heusser, Patricia Stutzmann Meier and Nadine McCallum ). 9 Resistance to glycopeptides ( Keiichi Hiramatsu ). 10 Resistance to other agents ( David C. Hooper and Jacob Strahilevitz ). Laboratory Studies. 11 Issues in the identification and susceptibility testing of staphylococci ( Betty A. Forbes ). Section II: Epidemiology of Staphylococcal Infection. 12 Colonization with Staphylococcus aureus and the role of colonization in causing infection ( Henri A. Verbrugh ). 13 Epidemiology of community-associated Staphylococcus aureus infections ( Rachel J. Gorwitz and John A. Jernigan ). 14 Epidemiology of Healthcare-Associated Staphylococcus aureus Infections ( Andrew E. Simor and Mark Loeb ). 15 Epidemiology of Coagulase-Negative Staphylococci and Infections Caused by these Organisms ( Kathie L.Rogers, Paul D. Fey and Mark E. Rupp ). Section III: Diseases Caused by Staphylococci. 16 Staphylococcus Aureus Bacteremia and Endocarditis ( Zeina A. Kanafani, Sara E. Cosgrove and Vance G. Fowler Jr ). 17 Surgical Site Infections and Surgical Prophylaxis ( Deverick J. Anderson and Keith S. Kaye ). 18 Infections of Intravascular Catheters and Vascular Devices ( Hidetaka Yanagi and Robert J. Sherertz ). 19 Skin and soft tissue infections ( Martin E. Stryjewski, Esteban C. Nannini and G. Ralph. Corey ). 20 Central nervous system infections ( Karen L. Roos ). 21 Diseases of the Eye ( Linda A. Ficker ). 22 Osteomyelitis and Other Bone and Joint Infections ( Odette C. El Helou, Elie F. Berbari, and Douglas R. Osmon ). 23 Staphylococcal Pneumonia ( Ethan Rubinstein and Marin H. Kollef ). 24 Urinary tract infections ( S. Gatermann and Kent B. Crossley ). 25 Toxic Shock Syndrome ( Aaron DeVries ). 26 Toxin-mediated syndromes ( Tristan Ferry and Jerome Etienne ). 27 Staphylococcal Diarrhea and Enterocolitis ( Mark H. Wilcox ). 28 Infections in Immunocompromised Patients ( Lisa E. Davidson and Helen W. Boucher ). 29 Clinical Manifestations of Community-Acquired MRSA Infections ( Brian S. Schwartz and Henry F. Chambers ). Section IV: Prevention and Treatment of Staphylococcal Infections. 30 Elimination of S. aureus carriage: Importance and strategies ( Loreen A. Herwaldt and John M. Boyce ). 31 Treatment of Staphylococcal Infections ( Kent B. Crossley and Joseph John ). 32 Vaccine-based strategies for prevention of Staphylococcus aureus infection ( Adam C. Schaffer and Jean C. Lee ). Index.