Design and Analysis of Clinical Experiments

Clinical experimentation is a systematic study designed to evaluate a product using human subjects. Design and Analysis of Clinical Experiments Second Edition presents the most up-to-date, classical and provocative content related to the design and analysis of modern-day clinical experiments. This second edition focuses on principles of design and analysis useful to studies on human subjects and includes new coverage of randomization, generalized estimating equations, and missing data, as well as a host of updated examples and numerical exercises, making it a must-read for clinical investigators, biostatisticians, and graduate students.