Bisphosphonate Bone Disease 3e

This is a new edition of Dr. Herbert Fleisch's textbook and reference on bisphosphonates and their use in treating diseases of bone and calcium metabolism. It is the only reliable, detailed book in which practitioners can quickly find clinically useful information on all bisphosphonates. It opens with an overview of bone and mineral metabolism followed by comprehensive coverage of bisphosphonate chemistry, mechanisms of action, pharmacokinetics, and animal toxicology. The rest of the book explains the clinical use of bisphosphonates in Paget's disease, osteolytic tumor bone disease, non-tumor-induced hypercalcemia, osteoporosis, heterotopic calcification and ossification, and other diseases, including chapters on adverse events and contraindications. The book also contains a table of the trade names of the commercially available bisphosphonates, registered indications, and available forms for each country.