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Textbook of Clinical Trials

Software / Digital Media
428 Seiten
2004
John Wiley & Sons Ltd (Hersteller)
978-0-470-02024-1 (ISBN)
342,72 inkl. MwSt
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A comprehensive volume on clinical trials that covers the important disease and therapeutic areas together with methodologies, phase I/II/III studies and other issues. It catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics.
This is a comprehensive volume on clinical trials that covers all important disease and therapeutic areas together with methodologies, phase I/II/III studies and other issues. The volume catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics. Cancer, cardiovascular disease, dermatological, dental, mental, ophthalmic health, gynaecology and respiratory diseases are all discussed in separate chapters, with discussions on outcome measures, competing risks and statistical models given for each therapy area. It also presents: a history of clinical trials; a summary of pertinent statistical issues; how to choose a clinical trial design; ethical constraints and considerations; clinical trial issues in paediatrics and those involving older patients; and, clinical trials in complementary medicine.

David Machin, Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore.Simon Day, Medicines and Healthcare Products Regulatory Agency, London, UK. Sylvan Green, Arizona Cancer Center, Tucson, Arizona, USA.

Contributors. Preface. INTRODUCTION. 1. Brief History of Clinical Trials (S. Day and F. Ederer). 2. General Issues (D. Machin) 3. Clinical Trials in Pediatrics (J.P.E. Karlberg). 4. Clinical Trials Involving Older People (C. Jagger and A.J. Arthur). 5. Complementary Medicine (P.C.Leung). CANCER. 6. Breast Cancer (D.A. Barry, T.L. Smith and A.U. Buzdar). 7. Childhood Cancer (S.B. Murphy and J.J. Shuster). 8. Gastrointestinal Cancers (D. Sargent, R. Goldberg and P. Limburg). 9. Haemotologic Cancers (C.A. Schiffer and S.L. George). 10. Melanoma (P. Y. Liu and V.K. Sondak). 11. Respiratory Cancers (K. Kim). CARDIOVASCULAR. 12. Cardiovascular (L. Friedman and E. Schron). DENTISTRY AND MAXILLO FACIAL. 13. Dentistry and Maxillo facial(M Wong, C McGrath and E Lo). DERMATOLOGY. 14. Dermatology (L. Naldi and C. Minelli). PSYCHIATRY. 15. Overview (B.S. Everitt). 16. Alzheimer's Disease (L.J. Thal and R.G. Thomas). 17. Anxiety Disorders (M.K Shear and P.W. Lavori). 18. Cognitive Behaviour (N. Tarrier and T. Wukes). 19. Depression (G. Dunn). REPRODUCTIVE HEALTH. 20. Contraception (G. Piaggio). 21. Gynaecology and Infertility (S. Bhattacharya and J. Mollison). RESPIRATORY. 22. Respiratory (A. Kallen). Index.

Erscheint lt. Verlag 21.6.2004
Verlagsort Chichester
Sprache englisch
Maße 200 x 253 mm
Gewicht 1070 g
Themenwelt Mathematik / Informatik Mathematik
Medizin / Pharmazie Medizinische Fachgebiete
ISBN-10 0-470-02024-5 / 0470020245
ISBN-13 978-0-470-02024-1 / 9780470020241
Zustand Neuware
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