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Encyclopedia of Bioinformatics and Computational Biology

Media-Kombination
3700 Seiten
2025 | 2nd edition
Elsevier - Health Sciences Division
978-0-323-95502-7 (ISBN)
2.869,95 inkl. MwSt
Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery. In the era of molecular diagnostics, targeted drug design and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can find us better prepared for such future events. This Encyclopedia comprises three sections, covering Theory, Topics and Applications. The theoretical methodology underpinning BCB are described in the Theory section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked "how to" questions. ???????Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definition of terminology, and lucid explanations by field experts.

Shoba Ranganathan holds a Chair in Bioinformatics at Macquarie University since 2004. After a PhD from the Indian Institute of Technology Delhi, India, in 1983, she took up a post-doctoral position in France. She has held research and academic positions in India, USA, Singapore and Australia, as well as a consultancy in industry. She hosted the Macquarie Node of the ARC Centre of Excellence in Bioinformatics (2008-2013). She was elected the first Australian Board Director of the International Society for Computational Biology (ISCB; 2003-5), President of the Asia-Pacific Bioinformatics Network (2005-) and Steering Committee Member (2007-12) of Bioinformatics Australia. She also serves as Co-Chair of the Computational Mass Spectrometry (CompMS) initiative of the Human Proteome Organization (HuPO), ISCB and Metabolomics Society. Shoba’s research addresses several key areas of bioinformatics to understand biological systems using computational approaches. Her group has achieved both experience and expertise in different aspects of computational biology, ranging from metabolites and small molecules to biochemical networks and pathway analysis. Her group’s current areas of research are protein-protein interactions, structure-based immune epitope prediction, host-parasite interactions and secretome analysis. She has authored as well as edited several books in Immunoinformatics, and contributed several articles to the Encyclopedia of Systems Biology, published by Springer in 2013. Mario Cannataro is a Full Professor of computer engineering at the University "Magna Græcia" of Catanzaro, Italy, and the Director of the Data Analytics Research Center. His current research interests include bioinformatics, health informatics, artificial intelligence, data mining, parallel computing. He published three books and more than 200 papers in international journals and conference proceedings. Mario Cannataro is a Senior Member of ACM and a Member of the Board of Directors of ACM SIGBio, a Senior Member of IEEE, a Member of IEEE Computer Society, and a Senior Member of BITS (Italian Bioinformatics Society). Mohammad Asif Khan is Associate Professor at the School of Data Sciences, Perdana University, Malaysia. He is also a recipient of the “International Fellowship for Outstanding Researchers” and Visiting Professor at Bezmialem Vakif University, Turkey. He was the Founding Dean of the School of Data Sciences and Founding Director of the Centre for Bioinformatics, both at Perdana University. He completed his PhD at National University of Singapore and before moving to Malaysia was appointed faculty at Johns Hopkins University School of Medicine, USA. His research interests are in the area of biological data warehousing and applications of bioinformatics to the study of immune responses, vaccines, inhibitory drugs, venom toxins, and disease biomarkers. He is President of the Asia-Pacific Bioinformatics Network, an executive board member of the Global Organisation for Bioinformatics Learning, Education and Training and Vice President of the Association for Medical and BioInformatics, Singapore

The new edition comprises the same three sections as the first edition, namely Methods, Topics and Applications, albeit thoroughly updated and enhanced.

I. Methods
1.Algorithms
2.Artificial Intelligence and Machine Learning
3.Biological Networks
4.Biostatistics
5.Data Mining and Integration (integrative Bioinformatics)
6.Ontology
7.Pathways
8.Text Mining
9.Epidemiology and Pandemic surveillance
10.Bioimage Analytics

II. Topics
1.Cheminformatics
2.Disease Informatics
3.Environmental (Biome) Informatics
4.Functional Genomics
5.Genome Informatics
6.Immunoinformatics and Vaccinology
7.Molecular Phylogeny
8.Proteome Informatics
9.Structural Bioinformatics
10.Systems and Synthetic Biology
11.Translational Bioinformatics
12.Bioimage Informatics
13.Interactomics
14.Epidemiology

III. Applications
1.Bioimage Analysis
2.Biome mapping and ecological modelling
3.Database Searching
4.Drug Design
5.Sequence Analysis
6.Predicting RNA structure
7.Protein Structure Prediction
8.Genome Analysis
9.Genome Editing
10.Genome-Wise Association Studies (GWAS)
11.Epigenomic Analysis
12.Transcriptome Analysis
13.Phenome Analysis
14.Proteome Analysis
15.Interactome Analysis
16.Phylogenetic Analysis
17.Vaccine Design
18.Infection Diffusion and Public Health

Compared to the 1st edition, the new edition includes 20-25% new content. About 10% of the existing chapters are deleted, and each of the three sections includes ~25 new chapters.
The three Editors in Chief will also perform the role of Section Editors; all submitted content will be reviewed by the three Editors.
Shoba Rangananthan was one of the EiCs of the previous Edition; Mario Cannataro was Section Editor for Methods and Asif Khan for Applications.

Erscheint lt. Verlag 16.1.2025
Mitarbeit Chef-Herausgeber: Shoba Ranganathan, Mario Cannataro, Mohammad Asif Khan
Verlagsort Philadelphia
Sprache englisch
Maße 216 x 276 mm
Gewicht 450 g
Themenwelt Informatik Weitere Themen Bioinformatik
ISBN-10 0-323-95502-9 / 0323955029
ISBN-13 978-0-323-95502-7 / 9780323955027
Zustand Neuware
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