Caspases as Molecular Targets for Cancer Therapy

Dr. Ankur Vaidya obtained his PhD from Dr. H.S. Gour University, when he researched design, synthesis, and screening of a few quinoline and oxadiazole derivatives for anticancer activities. He has 12 years of experience in teaching and research, and already supervised 18 PhD students. He wrote 5 book chapters and co-authored 2 books, including Nanotechnology Applications for Cancer Chemotherapy (Elsevier, 2020).

1. Introduction to Caspases, its function, mechanism, and classification
2. Mutations within apoptosis gene and caspases
3. Inflammatory caspases -1, -4, and -5 and their role in anticancer activity
4. Caspase-2 and tumor suppression
5. Caspase-3: A promising target for anticancer agents
6. Caspase-7 mutations and its activators
7. Re-instating the expression and activation of caspase-8 and caspase-10 in cancer therapy
8. Caspase-9 gene mutation and its activators
9. Caspases activity assay procedure
10. Current and future prospective of caspases targeting in cancer therapy