Computational Modelling of Tissue Surgery

Chapter 1: Mechanobiology of bone regeneration and bone adaptation to achieve stable long-term fixation of endosseous implants Introduction; Bone regeneration; Bone adaptation; Conclusion Chapter 2: Computational simulation of trabecular surface remodeling using voxel finite element method Introduction; Method of voxel finite element simulation for trabecular surface remodeling; Functional adaptation of cancellous bone in proximal femur predicted by trabecular surface remodeling simulation; Trabecular surface remodeling simulation for cancellous bone using microstructural voxel finite element models Chapter 3: Patient specific bone and joints modeling and tissue characterization derived from medical images Introduction; Methods; Applications; Discussion; Conclusions and perspectives Chapter 4: A coupled mechanical-biological computational approach to simulate antiresorbtive-drugs effects on osteoporosis Introduction; Bone histomorphometrical values; Biphosphonates: Alendronate; Proposed model; Results; Conclusion Chapter 5: A computational model to analyze the bone behaviour after a Total Hip Arthroplasty Introduction; Bone remodeling model; Bone remodeling around implants; The ingrowth control; Numerical implementation; Results; Discussion Chapter 6: Numerical simulations can influence and undermine the reliability of results in THR Introduction; Influence of finite element and mesh density; Physiological loading and relevance of muscle simulation; Constrained versus unconstrained femoral head; Physiological loading of the implanted femur; Concluding remarks Chapter 7: Structural analysis for pre-surgery planning: two applications in dentristry and urology Introduction; Dental biomechanics; Pelvic floor biomechanics; Conclusions Chapter 8: A numerical evaluation of the posterior cruciate ligament reconstruction on the biomechanics of the knee joint Introduction; Previous works on PCL; Numerical model of the knee joint; Results; Discussion Chapter 9: Tissue modeling and visualization using virtual reality Introduction; 3D data visualization; Medical image segmentation; Scene navigation; A simple prototype of virtual reality workbench Chapter 10: Biomechanics and the cyber-infrastructure: delivering the bone and other models to the surgeon Introduction; Bone remodeling algorithms; Using FE to create a virtual muscle; An overview of the CI; An implementation of a CI for biomechanics; A call to action