Bayesian Adaptive Design for Immunotherapy and Targeted Therapy
Seiten
2023
Springer Verlag, Singapore
978-981-19-8174-6 (ISBN)
Springer Verlag, Singapore
978-981-19-8174-6 (ISBN)
This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.
| Erscheinungsdatum | 22.04.2023 |
|---|---|
| Zusatzinfo | 50 Illustrations, color; 8 Illustrations, black and white; XI, 262 p. 58 illus., 50 illus. in color. |
| Verlagsort | Singapore |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Mathematik / Informatik ► Mathematik ► Statistik |
| Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik | |
| Medizin / Pharmazie ► Medizinische Fachgebiete | |
| Schlagworte | Adaptive clinical trial design • Delayed outcomes • Late-onset outcomes • Markov Chain Monte Carlo (MCMC) method • Missing data analysis |
| ISBN-10 | 981-19-8174-4 / 9811981744 |
| ISBN-13 | 978-981-19-8174-6 / 9789811981746 |
| Zustand | Neuware |
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